Abstract: Lung cancer is one of the most increasing diseases in the rapidly changing world. This disease can be cured in the initial stage. It should be identified at the early stage for diagnosis purposes. The prediction of lung disease stages can be done using image processing techniques. The proposed algorithm consists of a segmentation process using Dual-Tree Complex Wavelet Transform (DT-CWT). The segmented lungs are subjected to the feature extraction process which includes the Gray Level Co-occurrence (GLCM) algorithm....
4 Pages
1592 Words
Ovarian cancer (OC) is one of the important causes of death within gynecological tumors in the western world, with a 5-year survival rate of approximately 30% in advanced-stage disease(152). About 10-15% of all OC patients report a positive family history of the disease and can be included as “familial ovarian cancer (FOC).(11,12) FOC patients were defined as those with a history of ovarian cancer in two or more family members or in combination with common cancer diagnosed at a young...
2 Pages
877 Words
Abstract Female non-smokers face a much higher risk of death from lung cancer over the last few years. Many causes explain why lung cancer rates have skyrocketed among the women non-smokers. The increase in mortality risk from lung cancer in female never-smokers can be due to causes including environmental tobacco smoke, radon(a radioactive gas found in nature in soil and rocks)asbestos, outdoor and indoor air pollution. This literature study has shown that in addition to these cases it is likely...
3 Pages
1274 Words
Biomarkers are small protein or peptide molecules which are part of cell receptors, cell signalling molecules involved in cell-cell signalling or cell protein kinase activation and transfer of signal to the nucleus with the regulation of gene transcription. Biomarkers have functional significance in the recognition of different stages of cancer, therapy for cancer, and identification of different types of cancer of different organs according to the biomarker present. It is also used for the diagnosis and analysis of mutations in...
4 Pages
1941 Words
1. Introduction. With cancer affecting 1 in 7 men in South Africa (SA) during their lifetime prostate cancer (PCa) is the no. 1 cancer that affects SA men, It is estimated that 1 in 18 SA men will develop prostate cancer according to the National Cancer Registry of South Africa. (NCR-SA, 2014). Prostatic adenocarcinoma (typically called “prostate cancer” or “prostate carcinoma”), a malignancy of prostate gland epithelial cells, accounts for all but a tiny fraction of prostatic malignancies. (NCR-SA, 2014)...
4 Pages
1644 Words
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Why was this study ⁇ As cancer, one of the leading cause of death worldwide, with lung cancer being the second most significant diagnosed cancer in both men and women in US [ref] and the dismal five year survival rate of 16% is in part due to lack of symptoms during early stages and lack of effective screening test until recently [ref]. Hence detection at the earliest may decrease the mortality rate. Tumor staging based on coarse and discrete stratification...
6 Pages
2765 Words
Abstract— Breast Cancer is one of the most common disease that is responsible for a high number of deaths every year. Despite the fact that cancer is treatable and healable in earliest stages, A huge number of patients are examined with cancer very late. Data mining process and classification are efficient way to categorise the data particularly in medical fields, where those approaches are broadly used in diagnosis to make decision. Mining provides useful information from the huge volume of...
5 Pages
2130 Words
Analysis towards Melanoma Abstract— Melanoma is only harmful in human epidemic diseases and the level of these diseases is increasing continuously. Computers are not more intelligent than humans, but it is easy to find some information easily, which may not be easily apparent to the human eye. Such as: skin color variations or taxa variations. As knowledge is in inadequate source, automated systems proficient of detecting disease could save lives, reduce unnecessary biopsies, and reduce costs. My research is based...
8 Pages
3657 Words
Introduction: Melanoma and non-melanoma skin cancer are the most common type of malignancy in the Caucasian population (1-10). The incidence of both MM and NMSC is on the rise ,with an annual increase in MM of 0.6% among adults over 50 years (11). The incidence of melanoma may be even higher than indicated, as the national cancer registries has reported an underestimation of its incidence in certain countries. Consistent epidemiologic and experimental studies have demonstrated that UV-emitting tanning devices cause...
7 Pages
3208 Words
Introduction: [bookmark: _Hlk3485638]Imaging modality plays a great role in treatment planning. Positron emission tomography PET has been used in treatment planning in the delineation of Gross target volume GTV which is considered as the most important component in treatment planning. Also, PET Accuracy in the delineation of GTV impact on dose delivery to tumor tissue while delivering a low dose rate to healthy tissue or critical structure surrounding the tumor. PET has great sensitivity and specificity in the delineation of...
6 Pages
2919 Words
Abstract— Skin lesions are significant in determining dermatological medical conditions globally. Early diagnosis of malignant melanoma by dermoscopy imaging considerably will increase the survival rate. Throughout this paper, we tend to present deep learning-based approaches to resolve 2 issues in skin lesion analysis employing a dermoscopic image containing the tumor. Estimation of these biomarkers are wont to give some insight, whereas detecting cancerous cells and classifying the lesion as either benign or malignant. This paper presents groundwork for the detection...
8 Pages
3467 Words
Introduction High treatment costs, strenuous treatment plans, and emotional stress on the patient and on her family are the burdens women with breast cancer have to handle. Breast cancer is the most prevalent cancer among women in the US with 245,299 new cases and 41,487 deaths as a result in 2016 with higher rates present in both cottonwood county and in Minnesota (USCS, n.d.). This paper will evaluate the prevalence of breast cancer in Minnesota and Cottonwood county. It will...
4 Pages
1784 Words
Introduction The advancements in NGS technologies and the emergence of Omics field has led to the development of various approaches in studying cancer. The common approaches to identify molecular mechanisms in cancer include scanning the genome for cancer-specific mutations, exploring differential expression of mRNA through transcriptomics or that of protein through proteomics [Chakraborty S et al. (2018)]. However, limiting the analysis to only one type of data is not very efficient because it does not provide a holistic view of...
4 Pages
1914 Words
Introduction Ovarian cancer (OC) is the 9th most common cancer and the 9th most common cause of cancer-related death in women, with an overall 5-year survival of approximately 40%. In 2018, 295,414 new cases of OC were documented worldwide, 184,799 of which resulted in death (1). High-grade serous ovarian carcinoma (HGSOC) is the most common and deadliest subtype of epithelial ovarian cancer (EOC), accounting for 70-80% of OC deaths (2). Originating from premalignant lesions in the epithelium of the fallopian...
2 Pages
1126 Words
Introduction Prostate cancer is the second most frequently diagnosed cancer in the world.1 Androgen deprivation therapy is the main treatment for advanced disease. Androgen deprivation therapy (ADT) is a temporary measure but can accelerate osteoporosis, and bone metastases are common in advanced prostate cancer and are associated with significant morbidity, including pain. All patients eventually develop castration-resistant prostate cancer (CRPC). CRPC patients had a poor prognosis, with a median survival of about 18 months.2 Clearly, new drugs are needed to...
4 Pages
1899 Words
Introduction Drug discovery and development involve a number of stages to develop a novel drug, therefore a reduction in time frame new approach is developed which is repurposing of existing drugs. Till to date, the importance of drug repurposing is significantly increased to identify new use of the pre-existing drug. Repurposed of the drug can be achieved by two methods, one is unintentionally and another by systemically (Parvathaneni, Kulkarni, Muth and Gupta, 2019). Drug repurposing is one type of drug...
6 Pages
2506 Words
ABSTRACT Cancer is the disease that results when cellular changes cause the uncontrolled growth of cells. Cancer causes fast cell growth. There are several causes of cancer, and few are preventable. Genetic factors also cause the cancer. Cigarate smoking, lot of alcohol consumption, excess weight, physical inactivity and poor nutrition, these causes cancer and these are preventable causes. The chances of developing cancers may be reduced by not smoking, maintaining a healthy weight, not drinking lot of alcohol, eating lot...
2 Pages
1052 Words
Abstract Cancer is a frightful disease and represents one of the biggest health-care issues for the human race and demands a proactive strategy for cure. Exploration of natural product containing anticancer agent provide a promising line for research on cancer. Moringa plant (Moringa oleifera) is one of the medicinal plants used in traditional medicine for the treatment of cancer. Several studies have reported that water and alcoholic leaves extracts of M. oleifera have anticancer activity in some cancer cell line,...
4 Pages
1901 Words
Abstract Plant tissue culture is a collection of techniques used to grow plant cells, tissue, organs and their components under defined physical and chemical conditions in vitro. Plant tissue culture used to create large number of clones from a single explant and it is easy to select the desirable traits. Plant tissue culture technique is very helpful in genetically modified. In addition, we can do this technique at a very short time and small spaces. Therefore, the plant tissue culture...
3 Pages
1305 Words
Genetic therapy is the use of the delivery of nucleic acid regeneration cells to a patient's somatic cells to prevent or treat the disease. In the last few years, much research has been done worldwide in the field of genetic cancer treatment. In the current situation, there are many types of cancer treatments like viral replication, tumor suppression, tumor immunogenicity, suicidal gene therapy, etc. Cancer is a disease caused by mutations in cells that remain unprotected and lead to cell...
2 Pages
1010 Words
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Popeye domain-containing (POPDC) proteins are effector proteins that bind to cAMP to create a second messenger response that can influence the behaviour of cancer cells (Amunjela & Tucker, 2016). There are three different genes POPDC1, POPDC2 and POPDC3 that encode these proteins, however only POPDC1 and POPDC3 have been related to cancer cell behaviour. POPDC1 and POPDC3 are organised in tandem on chromosome 6q21 and POPDC2 can be found on chromosome 3 (Andree et al., 2000). All three of these...
3 Pages
1400 Words
Normally people use to intake food for being active and to make the bodywork properly. People used to take hygienic and natural types of food for getting a cure for diseases. Some disease is getting a cure by taking of health food items. The food habit creates immunity power to fight against the virus or bacteria which affect the body cells. Every day the body cells need the energy to do their regular work. One of the dangerous and deadly...
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521 Words
In cancer research, viability tests are immensely significant. These tests are used to observe the characteristics of different kinds of cancer. In drug development, viability of hostile cells are tested against chemical substances to evaluate the potential of those substances in pharmaceutical use. Additionally, the adequate dosage for those drugs are also studied in vitro. Established in 1977 from a patient with acute myeloid lymphoma in the National Cancer Institute in the United States, human Caucasian promyelocytic leukemia (HL-60) cells...
4 Pages
1888 Words
In recent years, AI has gradually entered the medical field. Artificial intelligence continues to break through the sensitivity and specificity of machine-assisted diagnosis at the 'digital' level, and exerts its value in multiple scenarios. However, many products are still far from large-scale clinical applications, and it is not easy to obtain the approval of clinicians. For the big names in the medical profession, whether the ability of AI really reflects the value clinically is the key point. From February 21...
2 Pages
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Introduction As a point of departure, to understand how a tumour appears in our lungs we have to know how is our lungs anatomy. As we all know, the lungs are two organs located in the thorax and they carry out the breathing. They are separated by an area called mediastinum, where the heart, trachea, esophagus and blood vessels are founded. The air reaches the lungs through the trachea which is divided in tow principal bronchus, one on the right...
2 Pages
1130 Words
Breast Cancer is a common cancer in Hong Kong. It can be divided into invasive and non-invasive (Akram, 2017). Breast cancer does not only exist in females, but also exist in males. According to the Centre for Health Protection, there are total 4108 females and 15 males who are diagnosed in breast cancer respectively in 2016. The morbidly rate in females is more serious than males. Among females, breast cancer has become the third leading cause in Hong Kong. When...
2 Pages
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ABSTRACT Rise in deaths due to prostate and breast cancer are expected to continue in future. These diseases are the most common types of cancer for men and women across the globe. Machine Learning can be used to drop the number of deaths by these diseases with early detection. One of them is the classification of data of prostate cancer and breast cancer. The Cancer data which has been used has a variety of features, but not all features are...
3 Pages
1370 Words
Introduction This essay will seek to discuss the role of androgen receptor therapy in advanced prostate cancer. Prostate cancer and the androgen receptor (AR) will be discussed, namely the origins of androgen receptor targeted therapy, its development and role in treatment of advanced prostate cancer today, and the future of targeted therapy. Androgen receptor targeted therapy is utilised in advanced prostate cancer to improve morbidity and mortality. The role of AR targeted therapies have evolved over the past 80 years...
4 Pages
1910 Words
Breast cancer is a form of cancer most common in women, but can also affect men, were cells in the breast tissue become mutated and multiply. This most commonly occurs in cells around the milk ducts and glands. In the first stages there are usually no symptoms but, as cancer develops the size or shape may change and a lump could form. Some forms of this cancer are seen as hereditary due to mutated genes being passed on from the...
4 Pages
1700 Words
Meg, age 50, currently on post-menopausal, was diagnosed with Invasive Ductal Carcinoma (IDC), also known as one of the most common forms of breast cancer (“Invasive Ductal Carcinoma,” n.d.). The first sign of cancer was detected through a mammogram, followed by a physical examination and later confirmed by an ultrasound and biopsy. Three tumours/ lymph nodes were discovered. After surgery, Meg underwent treatments of chemotherapy followed by Taxotere, radiation therapy and hormone therapy. Side effects of treatments Chemotherapy & Radiation...
3 Pages
1380 Words