University:
California State University, Northridge
Course:
NURS 315 | Pharmacology
Academic year:

2025
Views:

202

Pages:

1
Author:

Brooke Howard

ACTIVE LEARNING TEMPLATE: Medication Brooke Howard STUDENT NAME _____________________________________ Tobramycin (Inhalation and IVPB) MEDICATION __________________________________________________________________________ REVIEW MODULE CHAPTER ___________ Aminoglycoside antibiotic CATEGORY CLASS ______________________________________________________________________ PURPOSE OF MEDICATION Expected Pharmacological Action Tobramycin inhibits bacterial protein synthesis by binding to the 30s ribosomal subunit, leading to cell death. Therapeutic Use Treatment of pulmonary infections in cystic fibrosis; serious Gram-negative bacterial infections. Complications Nephrotoxicity, ototoxicity, neuromuscular blockade, hypersensitivity reactions, superinfections. Medication Administration -Nebulizer twice daily for 28 days on, then 28 days off -Dose based on weight and renal function; infused over 30-60 minutes Contraindications/Precautions -Renal impairment -Pre-existing hearing loss -Neuromuscular disorders -Pregnancy Interactions Nursing Interventions -Monitor Peak/trough levels -Monitor renal function and hearing -Encourage fluids -Monitor respiratory function -Increased risk of nephrotoxicity with other nephrotoxic drugs -Caution with neuromuscular blockers, cephalosporins Client Education Evaluation of Medication Effectiveness -Decreased symptoms of infection -Improved respiratory status -Negative sputum or blood cultures ACTIVE LEARNING TEMPLATES - Complete full course -Report hearing loss, dizziness, or urinary changes -Proper use of nebulizer -stay hydrated THERAPEUTIC PROCEDURE A7