CRISPR BIOTECHNOLOGY
Neh, Sean, Thisanth, Midhushan, Phillip
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Introduction & How it Works
Disadvantages
CRISPR (Clustered Regularly Interspaced
Disadvantages of using CRISPR include:
Short Palindromic Repeats) is a powerful
Off-target effects: Might accidentally cut unintended
DNA.
gene-editing tool that allows scientists to
Ethical issues: Designer babies, modifying embryos.
alter DNA sequences with precision.
Long-term effects unknown: Edits might affect future
generations.
How it works:
Accessibility: May widen inequality if only wealthy
1. Scientists design a guide RNA to
groups access it.
match a target DNA sequence.
Ecological risks: Releasing edited species could disrupt
2. The enzyme Cas9 cuts the DNA at
ecosystems.
the chosen spot.
3. DNA is either deleted, replaced, or
repaired.
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Social/Ethical Consideraton
Ethical debate: Should humans
02
Purpose & Application
actually alter the human germline?
Some religious/cultural groups may
Medicine: Correcting genetic
oppose modifying natural life.
disorders (e.g. sickle cell anaemia,
Could using CRISPR alter or increase
cystic fibrosis).
global inequality?
Agriculture: Creating disease-resistant
Altering even one organism, not only
crops, improving yield.
humans, can affect the species of the
Type a supporting statement here
organisms, causing drastic change in
the environment negatively.
Must consider regulations for each
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country as well. Some countries may
Advantages
ban editing embryos while some
countries may allow this for research.
Advantages include:
Highly precise - targets specific DNA
sequences.
Efficient and cheaper than older
technologies.
Potential to cure genetic diseases.
Could reduce reliance on pesticides
by making pest-resistant plants.
