University:
Eastern Kentucky University
Course:
CHE 105 | Chemistry for the Health Sciences
Academic year:

2021
Views:

38

Pages:

2
Author:

gildnar99xu

Creatinine Clearance Worksheet - Key 1. What is the formula for calculating creatinine clearance? CC (mL/min) = (UV/P) X (1.73/A) U = urine creatinine V = urine volume (mL/min) P = plasma/serum creatinine A = body surface area in square meters 2. A 48 year-old male patient submits a 24-hour urine for creatine clearance analysis. The volume of the sample submitted is 1580 mL. The urine creatinine is 120 mg/dL, and the plasma creatinine is 1.0 mg/dL. What is the creatinine clearance? Is it normal, decreased, or increased? U = 120 mg/dL V = 1580/1440 = 1.10 mL/min P = 1.0 mg/dL A = not provided assume 1.73 CC = (120*1.10/1.0) * (1.73/1.73) = 132 mL/min (Normal) 3. A 35 year-old female patient with a body surface area of 2.50 m2 has a plasma creatinine of 2.5 mg/dL, and in 1 hour produces 90 mL of urine with a creatinine concentration of 100 mg/dL. What is the creatinine clearance? Is it normal, decreased, or increased? U = 100 mg/dL V = 90/60 = 1.5 mL/min P = 2.5 mg/dL A = 2.50 CC = (100*1.5/2.5) * (1.73/2.5) = 60 * 0.69 = 41 mL/min (Decreased) 4. Calculate the creatinine clearance in mL/min using the following results obtained from an 18 year-old female in a creatinine clearance evaluation: Urine Creatinine: 84 mg/dL (U) Urine Volume: 1440 mL/24 hours (V = 1440/1440 = 1.0) Serum Creatinine: 1.4 mg/dL (P) Body Surface Area: 1.60 m2 (A) CC = (84*1.0/1.4) * (1.73/1.60) = 60 * 1.08 = 65 mL/min 5. A 60 year-old male of average height and weight is admitted to the hospital for renal function evaluation. His urine creatinine was determined from a volume of 600 mL collected over 12 hours to be 120 mg/dL, and the serum creatinine was determined to be 1.5 mg/dL. Calculate the creatinine clearance for this patient. U = 120 V = 600/720 = 0.83 P = 1.5 A = 1.73 CC = (120*0.83/1.5) * (1.73/1.73) = 66 mL/min

Creatinine Clearance Worksheet - Key

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