University:
Liberty University
Course:
NURS 325 | Nursing Concepts
Academic year:

2024
Views:

189

Pages:

4
Author:

Sheha A.

MYASTHENIA GRANIS wedkness" Myasthenia or gravis I weakness of means "grove muide O voluntary on Striated muscles of the body. Myasthenia gravis is a chronic autocarre disorder attelting - the neurorrwculas trans -ission of impulses in the voluntary mickey of the body His characterized by weaten & rapid fatigue of any of the musclesunde voluntary control, coftrol Neuromuscular disordes involve the muscles Ex-the nerves that control them. Causer & Risk Factor Myasthenia the gravis transmission muscles is caused by a defectin of nerve impulses to H occurs when normal communication blu the nerve and murde is interrupted of the beuromuscular junction - The place where nerves cells connect custh the murder the Control. • Unknown Lumors of thymus. • Thyroid gland abnormalities • Autoimmune attack. Thyrotoxicosis, GLE Thyrotoxicosis, RA, Myasthenic Crusis Clay result from. natural deterioration. chotional upset, URI Surgery, traurra & ACTH-therapy, Cholinergic Cousis. C Can result medication with anticholinergic drug cohich release too much acetylcholine NMT- from even Pathophysiology The body's immune system is activated ↓ Thymic lymphocytes produce receptor acetylcholine antibodies that attack the muscle membrane at the bot post synaptic mo Depletion of acetylcholine receptor at the NINJ Fewer receptors are available to combine with acetylcholine Lo trigger a murde action Potential; Preventa ↓ Deled in the transmission of impulses from nerves to murde cell Loss of voluntary muscle strength. Myasthenic Gravis C/M Breathing difficutty Chewing / Swallowing difficulty, • Difficulty in climbing stairs, Hing object or rising from a gelated position. Lurred Speech • Impaired Speech (Dyscortthria) A Droeping head. • Facial paralysis. • Easy-la-ligability chlange in voice • Difficulty in maintaining stady gait le eyelid drooping •Blurred Double vision (Diplopia) 0 Dyspnea Weakness in the arms, hands, tinger legs & neck. DIE H.C, P.E Neurological examination • Test to detect acetyl Choline antibodies. •CT/MRI Scan of the chest. • Repetitive nerve stimulation. • Single-liber electromyography (EMG) Tensila chemical ederophonium Ctensilon) is a time to a total of 10 mg 30'ser after inj, result ind although temporary, Improvement inmurce Strength Ederophonium acts to blockan ensyal that breaks down acetylcholine the chemical that transmits Gignal-from- herve ending. to muscle receptor sites Management 0 There is no Known cure for myasthenia • Cholinesterase inhibitor- Medicines such as pyridostigmine & Neostigmine can block. the of chemical that normally makes the muscle relax once they have cont -cted & provide symptomatic relict. • Medication to alter the immune system. Steroids Prednisolone or immunosuppresond drug Azathioprine) can damp docun the body's immune system Es reduce the production of antibodies that couse MG. • Plasmapheresis & immunoglobulin-therapyi If MG masde weakness blcome go severe that it causes dife threatening problems then plasmapheresis / IV immurloglobulio therapy can given. redbym compt redudes Symptom - Surgical removal of thymer some individual without thymoma & may cure some people, possibl by rebalancing the immune system. in