Post pituitary gland Nurohypophysail gland
Eetend From Hypothalamus.
★2 nucleus:-
Supra optic ADH UASaperssin.
Paraventricular Oxytocin.
*Nuropeptid Both 9.AA. Diffrent in 3,8 A.A.
ADHpheng lalanin, Arginin.
Oxytocin Isolevein, Levcin.
*Secreted By Direct order From Hypothalamus.
Al Storge in Axon knops in post pitutary.
BBound to plasma protien.
CIADH, oxytocin Similler Stracter So Similler function.
Regulation of ADH Secretion:-
plasma osmoloruty CosmoReceptor in Hypothalmus].
Tosmolarity plasma1ADH.
Ecf Volam By Atrial Baro Receptor Volum Receptor.
JADH.
Shock Bleeding Water IV.R PADH.
Dehydration
3) Stress TADH
RAAS BP
Renin Ang II
Aldestion
MADHIBP.
Hypothalmus, ADH↑
Blow
MADH.Plasma Volum 1.
Plasma osmolarity.
Urin Volum↓.
Urin osmolarity.
ADHVASO Perssin:
Action:-
Anti diretic "H" 1' water Reabsorption.
in Late Segment of Nephron. DCT, CT.CD. By V2 Receptor open (Aquparin 2) V2 R, Icamp. 2) Larg dose =>V.C =>B.P↑ By Vireceptor act By TIP3, IDAG.
3) Oxytocin like Action (Smooth muscle contraction)
GIT Colic Bronchus B.C_Utras contraction.
Hormones Acting on the Nephron./ Diuretics and Their Site of Action
ADH disorders:-
DiSecretion ADH (Daibitus Insepidus).D.I.
Type:- A) Nurogenic_central & Nephrogenic_perphral.
Symptom and Sign --D polyurea 2) poly Dypsia 3) Loss of Water Soluble Vit
effect of ADH therepy.
Oxytocin
Action:-
DFemale
Utric contraction (Smooth muscle contraction).
Oxytocin
* ejection or Excretion of milk Lactation.
2) male
eject and transport Sperm In Vasa Deffrance.
mgoepthail
cell contractio
3) ADH Like Action.