4. 15 Concentrations yielding acceptable risks:
a . benzene. oral, 10-5risk, potency= 2.9xL0-2 (mg/kg-d)-1
Risk= CDI x Potency
10. 5 =
C=
2L / d x C mg/L x3 50d/yr x3 0yr
2.9xIO•:
x
mg/kg - d
70kg x365d/yr x70yr
I0· 5 x70 x3 65 x70 =
-� 0. 03mg/ L
_
2 X 350 X. 30 X 2.9x.10 -
b. trichloroethylene in air, risk10-6. inhalation potency 13xIQ-2:
f
20 m 3 / d xC mg/m 3 x3 50d/yr x3 0 yr
l. 3 xlf 1
x
70kg x3 65d/yr x70yr
mg/kg - d
10· 0 x70 x 3 65 x70 ,, = _
3
C=
6 6xl0--' mg/m
20x 350 x 30 x l.3xIO-10. 6 =
c . benzene in air, risk 10-5, potency 2.9xio-2:
4.18 DDT in fish= C (mg/ L) x BCF (Ukg); from Table 4.12, BCF= 54,000Ukg
Risk= CDI xPotency
0.020mg/L x54,000 L/kg x 0.002kg/d
034
x
Risk =
=0.01
70kg
mg/kg-d
4. 23 Infiltration of 120m 3 /hr, 0.1mg BaP/cigarette,1cigarette per hour:
a . Find the steady-state concentration
Input rate= Output rate
1cig/hr x 0.1 mg/cig = 120m 3/hr xC mg/m 3
C = O. l/ 120 = 0.00083 mg/m 3
b. living for a year with a smoker.
mo
m�
I day
hr x365day
0.00083 �x20- x -- x8day 24hr
m
day
=l.lxlO�mg/kg-d
CDI =
70kg x365 d/yr x70 yr
Risk= CDI x Potency= I. lxI0- 6mg/kg-d x 6.11 (mg/kg -d)-1= 7x10-6