University:
College
Course:
College Nursing
Academic year:

2023
Views:

337

Pages:

2
Author:

Ramy M.

1-Drug A has an ED50 of 30 nM and a maximum effect of 95%. Drug B has an ED50 of 95 nM and a maximum effect of 100%. Drug C has an ED50 of 150 nM and a maximum effect of 40%. Which of the following is correct? A. B. C. D. Drug B is the highest efficacy Drug c is the most potent and has the lowest efficacy. Drug A is the most potent drug Drug B is the most potent drug 2- Which one of the drugs mentioned in Q1 has the maximum efficacy: A. B. C. D. Drug A Drug B Drug C Drug A and B 3- As regards the following figure, which of the following statements is correct: A. B. C. D. Drug A has the highest efficacy Drug C has the highest efficacy Drug B is the most potent Drug A is the most potent 4- As regards the previous figure, which of the following statements is correct: A. B. C. D. Drug C is a partial agonist Drug A is a partial agonist Drug B is an inverse agonist Drug C is a full agonist 5-Drug A induced a dose -induced increase in contractility of an isolated heart ( EC50 of 30 nM of a maximum effect of 100%). In the presence of drug X, drug A induced a dose induced contractility of isolated heart (EC50 of 90 nM of a maximum effect of 100%). In the presence of drug Y, drug A induced a dose induced contractility of isolated heart (EC50 of 60 nM of a maximum effect of 50%.Which of the following statements is correct? A. Drug X is a non-competitive antagonist B. C. D. Drug Y is a competitive antagonist Drug X is a competitive antagonist Drug X is a physiological antagonist 6-A competitive antagonist is : A. B. C. D. Irreversible Reduce the efficacy of an agonist Reduce the potency of an agonist increase the potency of an agonist