ACTIVE LEARNING TEMPLATE: Medication STUDENT NAME _____________________________________ Lisinopril 3 MEDICATION __________________________________________________________________________ REVIEW MODULE CHAPTER ___________ Antihypertensives CATEGORY CLASS ______________________________________________________________________ PURPOSE OF MEDICATION Expected Pharmacological Action ACE inhibitors block the conversion of angiotensin 1 to the vasocontrictor angiotension 2. Prevent the degradation of bradykinin and other vasodilatory prostaglandins. Lower of BP in hypertensive patients. Improve symptoms in patients with HF. Therapeutic Use Alone or with other agents in the management of hypertension. Captopril, enalapril, fosinopril. Reduce of the risk of death or development of HF following MI. Slow progression of left ventricular dysfuntion into over heat failure. Complications Dizziness, drowsiness, fatigue, headache, insomnia, vertigo, weakness, cough, dyspnea, hypotension, Chest pain, edema, nausea, diarrhea, vomiting, renal failure, myalgia, back pain, muscle cramps. Medication Administration PO (Adult) 10mg once daily, can be up to 20- 40mg/day. 5mg once daily may be titrated every two weeks up to 40mg/day. begin with 2.5mg once daily in patients with hyponatremia. Contraindications/Precautions Hypersensitivity, Renal impairment, hepatic impairment, hypovolemia, History of angioedema with previous use of ACE inhibitors for benazepril. Concurrent use with aliskren in patients with diabetes or moderate to severe renal impairment. Interactions Diuretics, Potassium sparing diuretics, Antacids, COX-2 inhibitors, sirolumus, everolimus, antigiotensin 2 receptor blockers, doxycycline, temsirolimus everolimus, Nursing Interventions Monitor BP and pulse frequently during initial dose adjustment and periodically during therapy. Notify health care professional of significant changes. Monitor frequency of prescription refills to determine adherence. assess patient for signs of antigioedema. May occur at any time during therapy. Client Education Evaluation of Medication Effectiveness Decrease in BP without appearance of excessive side effect, drecrease in signs and symptoms of HF, decrease in development of overt HF. Reduction of risk of death or development of HF. Decrease in progression of diabetic nephropathy. Reduction of risk of MI, stroke, or death from cardivascular. Instruct patient to take medication as directed at the same time each day, even if feeling well. Take missed doses as soon as possible but not if almost time for next dose. Caution patient to avoid salt substitute or foods containing high levels of potassium or sodium unless directed by healthcare professionals. Advise women of childbearing age to use contraception and notify healthcare professional if pregnancy is planned or suspended. Emphasize the importance of follow up examinations to monitor progress.

Human Growth and Development - Lisinopril

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