University:
North Seattle College
Course:
CHEM 255 | Biochemistry I
Academic year:

2023
Views:

23

Pages:

9
Author:

Christopher Brooks

Biological Oxidation Oxidation Reduction is defined as The as the loss for and Gain fe The e lost in the oxidation is accepted by asp acceptory which is said to be reduced. To • Thees the Oxidation - Reduction is a tightly Coupled Process TRON TRANSPORT Example in Biological System The oxidation of NADH to NAD FMN to FMNH2 coupled with the andy Glucose) melaton reduction rofction and nat ANADH + H+ e- rclassed thyouigh vaw, 24+ + 26- are tranferviet to NADH & FADH NAD+ FMNH NADT, FAD to produce tha EDOX POTENTIAL (Fo) pare they ch chain The Oxidation reduction potential (Redox potential) a redox a quantitative measure is a of the tendency of somated pair to lose or gaur energy A port of this The Gedox generedox paver are assigned specific potential (Eo Volta) at pH to standard to 250 • The more negative redox potential represente greater tendency to lose e- NAOH + M+ FADH TAITOCHONDRIA The mitochondria are the centres for metabolki oxidatur reactions to generate geduced coenzymes (NADH & FADH₂) which in turn, cure utilixed in ETC to liberate energy in the form of ATP. 7 The mt consists of 5 cdistinct parts These are outer membrane, the inner membrane, the cristac I the matrix INNER MITOCHONDRIAL MEMBRANE The ETC & ATP So synthesixing system are The inner mitochondrial membrane. located on > It is impermeable to ions (H+, K+, Nat) & small Molecules CADP, ATP). • This membrane is highly folded to form cristae 7 The Surface is greatly Quea innere mitochondrial membrane increased due to cristae The inner surfars of the inner mitochondral membrare possess specialized particle, the Callund phosphorylating subunits which are of ATP production. the cenbees in - The inner matrix is euch is exszymes, responude for citrus acid cycle, B-oxidaln of factly and & Eredeti of aa. The inner mital Complex 1, 11, 1 mem hou 5 Ive v enzyme complex Complere I-IV are of e- while complear is responsible for ATP synthesu. Besides these enzyme complemes there are certas mobile e- carriere in the respirabey chaus - these include NADH, Coenzyme Q, cyt c 202 The largest proportion of the oz supplied to the body is utilized by the mt for the operation of ETC