University:
Princeton University
Course:
CHM 345 | Biochemistry
Academic year:

2024
Views:

418

Pages:

8
Author:

Saien Moodley

Welcome to Biochemistry! Discover biochemistry: the chemistry that drives life processes. Explore molecules and their interactions in living organisms. Learn course goals and objectives. by Saien Moodley The Molecular Logic of Life Key Biomolecules Carbohydrates, lipids, proteins, nucleic acids form life's foundation. Monomers and Polymers Small units bond to create complex structures like proteins and DNA. Hierarchical Structure Atoms build cells, then tissues, culminating in whole organisms. Water's Role The universal solvent, crucial for molecular interactions and life. Protein Structure and Function Amino Acids Protein Folding Enzymes Building blocks linking to form diverse Shapes form in four structural levels, Biological catalysts speeding up Sequence determines protein shape Misfolding can cause diseases like Mechanisms involve active sites and proteins. and function. critical to function. Alzheimer's. reactions efficiently. substrate binding. Carbohydrates: Energy and Structure Types Monosaccharides, disaccharides, polysaccharides fuel energy and structure roles. Glucose Metabolism Pathways like glycolysis break down sugar for energy. Structural Role Cellulose and chitin form plant and insect frameworks. Glycobiology Carbohydrate signals regulate cellular communication. Lipids: Membranes and Energy Storage Fatty Acids & Triglycerides Phospholipids Steroids Main components of cell Hormones that regulate membranes forming bilayers. various cellular functions. Energy-rich molecules for Beta-Oxidation Process breaking fatty acids long-term storage. 2 1 for energy production. 3 4 Nucleic Acids: Information Storage and Transfer DNA & RNA Carry genetic information and direct protein 1 synthesis. 2 Replication & Transcription Copying DNA and making RNA transcripts. Amplifies specific DNA sequences for study and diagnostics. Flow from DNA to RNA to functional proteins. 3 4 PCR Technique Central Dogma 5 Translation Building proteins from RNA instructions. Metabolism: Energy and Pathways 1 Catabolism & Anabolism Breaking down molecules vs. building new ones. Metabolic Pathways 2 3 4 Glycolysis, Krebs cycle, oxidative phosphorylation generate energy. ATP The cell's main energy currency powering reactions. Regulation Enzymes and hormones modulate metabolism efficiently. Biochemistry in Action Medicine and Drug Discovery Target molecules for new treatments and therapies. Personalized Medicine Tailoring medical care to individual genetic profiles. Biotechnology & Agriculture Applying biochem to improve crops and industry solutions. Future Frontiers Innovations in research pushing the boundaries of health science.

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