Exam Readiness 2

Anemia in cancer patients can be a result of which of the following? (Select all that apply). Currently Selected: A, B, C A Loss of RBCS B Increased destruction of RBCS C Decreased production of RBCS D. inch repletion therapies Question 2 FLAG QUESTION Choose the drug or drugs that specifically target the neurotransmitter released by enterochromaffin cells after patients receive chemotherapy (Select all that apply) 5-HT3 receptors Currently Selected: C, D A Reglan B Emend C Ankyzeo Palonosetron D Anzemet bolaretion TK is a 32 y/o transgender female who received Cycle 1 Day 1 of investigational drug Xat 15:30 os 3/14/2022) If she then experienced an episode of emesis at 11:00 on 3/15/2022, which type of treatment induced nausea and vomiting did she experience? Currently Selected D A Anticipated B. Delayed 24 hrs after chemo C. Refractory Acute ≤ 24 hrs during or after chemo Your patient is on TPF (Taxotere, Paraplatin, and 5-FU) and develops a Hb 8.0 mg/dL. You start him on darbepoetin 160 mcg every week by SO injection. After 10 days his Hb is 9.0 mg/dL. You recommend to the medical oncologist that he Answers: A-D ↓dose 409. = giwe 600. VA Reduce the dose to 96 mog 160 x 0.6=96 mcg B Continue the same dose C Reduce the dose to 120 mog D Increase the dose to 200 mcg TI is a 72 y/o patient receiving docetaxel for prostate cancer. On Cycle 1 Day 1 of treatment his ANC is 1700. What term do we use to describe the lowest poet thr his ANC could reach in between cycles? Currently Selected C A peak 8 febrile neutropenia C nadir D myelotoxic portion Question 14 FLAG QUESTION from filgrastim can be prevented or minimized by prophylactic. Currently Selected: D A anemia, procrit B febrile neutropenia, pepcid C nausea, zofran D. bone pain, claritin A medical resident would like to give your patient IV Anzemet because she is experiencing vomiting during her chemo infusion. What is the correct course of action? For CINV PO only! Currently Selected. D A Change to Sancuso Granisetron (patch) B Change to IV Zofran C Dispense as written D Change to PO Arzemet Thr before Question 16 く FLAD QUESTION > ... Based on the information below, please determine if prophylactic colony stimulating factors are appropriate starting with Cycle 1 for patients receiving either Drug A or Drug B Currently Selected: D A Drug A Yes: Drug B. Yes B Drug A. Yes, Drug B No C Drug A, No: Drug 8. Yes D Drug A. No, Drug B, No Currently Selected: B A 1 and 3 B 1 and 2 C 2 and 3 D1.2 and 3 When counseling patient about THC containing products, please select the MOST correct statement. Currently Selected: D A Because patients can't technically overdose on THC, they can start at high doses and taper down if they need to B When patients buy CBD from the gas station, they-dent-wo-le-worry because the FDA regulates the industry C Because THC and CBD come from plants, there is ne-risk-of-interactions with drugs like warfarin. D When CBD is combined with THC in a product, the CBD can help to minimize the feeling of being "high" Any adverse event 401 (99.3) 223 (55.2) 191 (970) 96 (48.7) Diarrhea 327 (80.9) 52 (12.9) 105 (53.3) 17 (8.6) PPE syndrome 256 (63.4) 53 (13.1) 104 (52.8) 18 (9.1) Nausea 236 (58.4) 15 (3.7) 86 (43.7) 6 (3.0) Fatigue 182 (45.0) 19 (4.7) 85 (43.1) 8 (4.1) Vomiting 145 (35.9) 12 (3.0) 50 (25.4) 7 (3.6) Stomatitis 103 (25.5) 10 (2.5) 28 (14.2) 1 (0.5) Currently Selected: A VA Ondansetron 8 mg PO 30 minutes prior to Drag X B. Lorazepam 0.5 mg IV 30 minutes prior to Drug X Any Ca Chale C Fosaprepitant 150 mg IV 30 minutes prior to Drug X D. Otanzapine 10 mg PO 30 minutes prior to Drug X Please select the MOST correct statement. Currently Selected constipation/delayed gastno emptying A Metoclopramide can be used in patients who have diekee associated NIV B Olanzapine is a category 1 agent for breakthrough N/V and prophylaxis C Cannabinoids are net-sencidered-alflective to treat or prevent CINV Transing auton D Benzodiazepines like lonazepam, exert a direchantremetice elleet on the brain Your patient with Hb 7 g/dL will receive 2 units of PRBC. You expect that once the transfusion is complete, their new Hb value will be g/dl Currently Selected: C I unit = ↑ ~/g/dl A 8 B 10 C9 D 11 TC is due to receive his 2nd cycle of Cisplatin and Gemcitabine. He experienced nausea on the 5th through 7th day during the 1st cycle and is feartal of cooing in for anymore treatment. Which medication would be MOST helpful for him to take the night before his next cycle? anticapitory Currently Selected B A Aprepitant before anticancer B Olanzapine treatment C Ondansetron D Lorazepam A new drug is being studied at your institution and the protocol indicates that it causes nausea and vomiting 8% of the time. What Day 1 antiemetic prophylass regimen would you choose for patients with no additional risk factors Currently Selected C A ondansetron 16 mg PO Bondansetron 16 mg PO, dexamethasone 10 mg IVPB, and fossaprepitant 150 mg IVPB C no prophylaxis is needed at this time Dondansetron 16 mg PO and dexamethasone 10 mg IVPB Which of the following scenarios is associated with anticipatory nausea and vomiting? TA Currently Selected: A A A patient is recerving chemotherapy in a chaotc environment B A patient is 67 years old and has a remote history of depression C A patient who a remote history of obsessive compulsive disorder D A patient consumes three alcoholic drinks every day with dinner Your patient refuses any blood products for philosophical reasons. What are some strategies you can use to prevent anemia (SELECT ALL that arely) Currently Selected AD A Blood return systems B Withinolding chemotherapy C Frequent blood draws D Pediatric tubes E Aranesp Drugs like darbepoetin and epoetin may accelerate which of the following hallmarks of cancer? Currently Selected A A sustained angiogenesis (new blood vessels) B apoptosis C limitless replication D initiation suppression Your patient had a recent ENG due to a near syncopal event in their oncologists office The EKG was unremarkable and their baseline Q10 was sms which of the following SHT3 antagonists would you choose to give the patient to prevent chemotherapy induced nausea and vomiting? Currently Selected A A Palonosetron No QTC prolongation B. Dolasetron C Granisetron QTC Prolongation D Ondansetron Your patient calls the clinic to report feeling warm and tells you he has a "fever of 37.5 degrees Celsius" He has no other complaints except for feeling fatigun after chemotherapy. His labs were drawn earlier today. Based on his symptoms and lab values, what is your recommendation? WBC 5 ANC 1000 Hb 122 500 Cho neutropenia) HCT 33 PLT 123.000 Currently Selected: A FN: ANC 2500 2 38°C over Ihrs or 2 38.3°C next 48 hrs A Watch and wait because he does not meet the criteria for febrile neutropenia Binitiate prophylactic broad spectrum antibiotics and sagramostim impatient C Dose reduce his chemotherapy by 25% as secondary prophylaxis for next cycle D Administer sagramostim outpatient and tell him to take acetaminophen