Electrophilic and Nucleophilic Substitution

ACS EXA M Br i Bar createsalkenesfromannulhalides imation ramosmetad irector nossnits same Hainan turns is a metalc atalyst Halen an annuariaetoanaminegives ng man removesketonefunctional group whenaddedto anaminemakesit nos Frableto substitution formsmen canbereplacedbyat.cnor a atheuseof s it 1 it i it Is t y notzu is pale Éi it nite y 171 and naoet o o 1 to wao a Noren no can nor I in jsn If wit entslike cua can no sodasontoanaruinariaeButwill oat notreact a cyanide y Anos ton BE Yi q two to aoetoncucionexenescancreatealkenes Elman 171 using a metal catalyst Alkylation 6 Nitration at is El two arson mygtsn.tt want ayyy Eino Il YIO Elmo IT anas IvetteÉ manor I T 11 two area new ftp ITF r 1 The EE EE enameo i nor 171 e name s y ktruo off ÉÉo nothin Thor nor Inhibit Éilettome't aarson tons.IE Heros Thot ite it to with o m i 71 goon E i 71 17 E I I ans .mg to I I I ahh ngketonesmm Pcc tmmmamidesmnn gg yakkfidsumm on Liaworks alkanes NBS room T 1 city 1 at IT Br Ther cats 7mg Em II I É assoc I l Howito 0 inaniasadas a hydrogen thermo annulateketonesby using toright acleophinic carbonto attack coal cold electrophile i y no on warm is É s sitsEr kinetic newlycreatednucleophilicc arbon carbonyl grouporthe tacks samemolecule to produce a acarbon 4 not ma an so on o or a go prep0 É IL Ty Manta addstoleft Addition Aldol in the basewilla ttachalpha t mirrorimageattachedto It p EYE at nacn.it Hasou a en m I It pec 1 amine If III E Th Hao y I i maemoo 2acetone s not Him LDA removal of anhydrideto Hootoncont YEH sonto itsoy reduction I I on as I oh gup p identicalr eproduction o o o Aldol Condensation H og at o o A a in reactionsto alkynes acetylideannulation acetylideformation see a ri wants x I naam g ozonolysis o it on 4no tw n Bari Bitsthe on end v amonount Hoyts't x o markov end go.gg x arenadinaride carboxy harogenation Intramolecular Aldol o o on S gag at Eton Claisen Cond Ei I twoestersforminga betaketoester eto step strongbase is useddeprotonation aseremoves alphahydrogen steps nuc carbonattacks carbonyl a of Using LDAtoEsters carbon ok ns.naret.ms ethoxide stepu exo removescan carbon steps acidreacts a nucca my coach Ag no agone on H varsity on Enolates and Reactions o 1 I o naanscatsil abase thatwillremove oats be analpha hydrogen allowingitto susceptibletoannulation in is o o morestable a kinetic v Thermodynamic no t o s m y it it ok of it Eat side annulateto the left carbon iii leftalpha roomtemp ermo zs.cc alkylateto the rightside ÉÉÉ no o o i I iii f i I it Electrophilic and Nucleophilic Substitution 0 p rs M Pt akane s if OH War OR Nra Ion qtr alkyl j anyone OH Nr g roups sm talogens Oxidation and Reduction O u cc ialcohols res adenudes alcohols gives ketones R Ciality Napa o 2a Itai LEIF fit p IET t aime a annoy Ialcohols ve carboxylicacids alcohols gives It retones us Iii an one alcoholsto Garzon 6 carboxylic zero thy acids toy reacts a 1,2diols eavage of c c bonds me Tig a pec is.no neutralization IIIIiqgwamen.sn fat carboxylic acid 1 carbon a 2 carbon I ketone hes oxidation alcohol to carboxylic in no For gin Is t acid oh Hasou n Il aldehyde intermediate Synthesis and Quantitative Analysis reducesattunesto alkenes IFtiary EE t hezisomeris sunadditionand thesame nuarogenson isomer h asthe thecis side makesalkynevenerable produced nano tosubstitutionbyannulation not ien Hypo annoying.tl macetal protecting groupprotects aired orreduced acylchlorides rides HI Iiit ÉÉ Éto Éy annua aldenuaes alcohols ketones thioester ester amide carboxylatei on Ikoxymercuration m.IE I Ikene n alcoholforms an ester A At on c as II d the carbonylgroup is removed dtheendproducthas1 lesscarbon to amineusing toffman amideconditions and Bra in basic water curtius acylchloride to amine usingwars o water to D It Iggy on Ant Fyi Ioi was no ya a penna with 3 was a lactone pig Hao i