University:
Camosun College
Course:
NURS132 | Promoting Health and Wellbeing
Academic year:

2023
Views:

34

Pages:

3
Author:

Aysha A

PEPTIC ULCER DISEASE Chronic mucosal ulceration that penetrates musculoris mucosal Aflects Duodenum (Duodenal canew) or Stomach (gastric cancer) Pepsin Damasing Aid Preepithelial barrier -Mucas servetia (unstirred) Bicorbonate Creleased int unstirrel) Buffers the Htions Dumaging NSAIDS Cigarette smoky Alcoholis H.Pylori Hpracid Defensive Shock ischemia Epithelia barrie Delayed gastric emptying •Restitution - Resporation of damaged epithelium & Imucw Blood Flow allkaline PH •Regeneratia:- By Prostaglandins & EFS of Epithelium •Secretica of (prostaglandins - Gastriz mucosa secrete Pu which Inc. Blood Flod & epithelial cell Restituta subepithelial burrir Mucus Blood Flow - I Remove toxic metaboli 2) Bicabonates neutralize Acid 3) Suppd of mutrients/ Direct mucosul damage Pathogenesis gastre DH.pylori Antral + duodenal ulcers/ NSAIDS IPL I Bicrbonel cigarette Blood Flow 4) Alcohol Ho st 2) Detenz impaired Ischomic Shock Relayed gastric emptying Host Factors 5) Gastic hyperacidit: Zolling Ellison syndrome porietal cell hyprplasic H.pylon Imucin gathesis MORPHOLOGY GROSS Site-Anywhere IDuodenum: First part of duodenun stomach Leser curvature blw Junctia of Budy and Antun // Proximal ulcers Distal ulcers// Gastroesophaged junctia of orophagus Anastomotic site:-(distal gastric resection) Multiple ulcers =D/S/J Zollingy Ellison syndrome Number: Solitory (100%) Size Lesions-0.3 cm in diameter shallow 0.6cm in diamete Deep shape Round to oval, PUNCHED OUT DEFECT Morgins Peptic ular shap demarcation from the Surrounding mucosa Gastric mucosal folds can be traced to the margins. of ulcer and radiaty folds of mucose from ulex like spoke WHEEL Base smooth, clean - due to exudate/ MICROSCOPI aux Du NEGC Askanazy zones D Necrotic zone:- mosl-sup-zone 2) Sup-exudative zone: Fibrino puralent exudates with neutrophilic infitration aranulation tissue zone: infiltred & mononucler leucocytes Zone of cicatrization: Fibrous tissum or collagenous scar which form base of ulcer and may show mf.cells. Cronic, Reary, MORBID Your adults Epigashiz burns // 1-3 hn aftrmey 11-2 AM NJV, Bloaty, JWL. COPAPLICATIONS OF GASTRIC ULCERS Bleeding = 1 Cossof iron. Perforation = (~5% Patients & most commm complications) Pyloric obstruction was in prloric (100%) 2odeme Combined ulcers//