University:
Camosun College
Course:
NURS132 | Promoting Health and Wellbeing
Academic year:

2023
Views:

291

Pages:

2
Author:

Aysha A

SCQUAMOUS CELL CARUNOMA 11 Multifactorial disease seen in middb-aged many RISK FACTORS Tobacco products & smoking Increases the ofisk of tomorys of oral cavit Nicotine in tobaco&tobacos-related components Canur) Carcinogens Act as initiater & Promotes Non-smoka/SMOKELESS Smoking cigarette, bedes cigar, pipe sincoking, Feverse soloking. Inte form of Betel quid/pag slaked lime & tobacco Alcohol consumption Ether as cocarchogen or promoter. Risk is magnified (Who do bott other-Risk •Chronic tonitetion of mucosa •vit. A def & Immuno suppressica toor Netrition // PATHOGENESIS cequential andvation of oncogenes & inactivation of tumour suppress of genes. ✓ Inactivation of please gene (80% caves) stratified squamous epithelium undergoes (hyperplasia)/nypukeratosis Mutation of p53 tumour suppresser gerle is ass with progression of hyperplasia Amplification & Progression of cyclin D1gere activates Cell-cycle progression. MORPHOLOGY Site: Torgw> Lep Commonsites are (Lower lip, ventral surface of fingus, Flour of mouth Buccal mucosa, soft palate gingivall Gross Raised, Firm, poorly plaques, irregular, Roughened areas of mucosal thickening masses Laker ulcerated & protruding groy white matts, with irregular & rolled Bordir MICROSCOPY rang from well diff. the ratimizing neoplason to poorly differentiated anaplastic tumour. Local (Tisse) SPREAP Lymph (more on tvior node (Cervical node Corcinemas base of & orophagy ze tongue metastaze to deep retroperyal Lyoph nodes Blood spread LungLiver Bones/ Hoak sa cell cre seconng primy. Malignang" in Lunge & Graphag Verucas corcmona Site: Beccal mucosa & Lover gingiva EtiosAg (El) CowNts apper • fusy infitrah morgins/ MORPHOLOGY Grass: Lorge (Fungaing), soft papilley growth Microscopy Hyperkeratosis, acanthosis, & laenign-app papillomatosis Retes pegs swollen, voluminous extend deep.