University:
Camosun College
Course:
NURS132 | Promoting Health and Wellbeing
Academic year:

2023
Views:

77

Pages:

2
Author:

Aysha A

DEFINITION C/M Measels disease (Acute, high) contagious, charade by fever and resp. symptoms) foll. by maculopapules rash Incubation lo days Fever (10th dos) Prodormal stage Koplik-spots Bluish white spots on burcal, mucosa 2nd Lower molar hear fudes with Rach today Transmission:- Respiraty ERUPTIVE STAGE skin Rashes Maculoppular dusky Red Rashes -Droplats -Aerols Bohind the ears Face, Arm, trunk 4 Legs fade in the same order complications:- Otitis media Absent in HIV infected People 3) PANS System Complications Hetch's Pneumonia (Immunocomprised) 2) Selensi (S.S.P.E) 7-10 years SIS ELISA > PCR 3 Post-measels Stage weight loss & weakness Naccine Live vaccine Schwartz strain (Most typical) (MR) + MMR Lyophilized form reconslihs with distill Walk-wed within 4 hrs Edmonston-zagreb strain theimliable; -20°C 2 doses 9-12 months Complications D2 Bacterial infections 16-24 months fotitis media & Bronchopneumonia Failure of fever to subside with rash worsening of underlying Tuberculosis False Mantoux test ✓ Toxic shock synd 2) Complication due to Measels vinis itself Giant cell preumonitis (Hachts Pneumonia) +pla rrhoer Subacus sclerosing panencephalitis (SSPE) PATHOGENESIS DTransmission:- Respired Droplets -short distancer Route 3 Suspended Aerasds 2) spreads Local Respiraty Tract Regiond lymph nodes Bloudstream (Multiplies) via infected monocytes (iviremia) Reticuloendothelial system (multiplies) spills over to Blood (2° viremia) disseminates to various siter. seeded in Target site:- Epithelial surface of body, skin, respiratory tract & Conjunctiva LAR DIAGNOSIS o Specimen 1:- Nasopharygeul swab (othes comi), swab, blood, resp. secretions) arine • Antigen detection Using anh-nucleoprotein antibodies. CDirect immunofluoresal test) OVIRUS ISOLATION Cell lines:- Monkey or human kidney optimal for isolation of Measels virus. I of specimen into monkey or human kinly coll line, By inoculation of produces (CPE) as multinucleated giant cells (Warthin Finkeldey cells) Antibod-detection in serum - Against nucleoprotein antigen by ELISA ✓ det of IgM Raised titre of Anti-Measels antibod. • Reverse-transcription PCR:- Relect VIRAL RNA -RNA can be detecked in specimens up to 10-14 days post Rashes. Treatment symptomatie & s-py-measures. Vit A I Red morbidit & mortilib//.