Acute Myeloid Leukaemia (AML) - Edubirdie

University:
Camosun College
Course:
NURS132 | Promoting Health and Wellbeing
Academic year:

2023
Views:

53

Pages:

2
Author:

Aysha A

ACUTE MYELOGENOUS LEUKEMIA of progenits remling in Neplerome in the morrow. accumulation of armenenture di myeloblast 1 Adults aniet Abrupt Symp. Rel to dep marrow Function BONE MARROW FAILURE Anemia Forlige & Weakness Areutropenia Inrombaytopenia BONE PAIN & TENERNERS. Extramedully Infitration ✓Gingival hypert Hepato splenomegaly LAB FINDINGS PERIPHERAL BLOOD Total WB ccount: Raised, 20x10 1L to 100 x10/L WEC ↑ Hemoglobin : Decreased, 5 to 9 g/dL HS ↓ CLINKAL FEATURES PERIPHERAL SMEAR RBC:- Normocytic nermochromic Anemia WBC- Total WBC count markedly increased. (20% myeloid Blast) 3 to 5 times longer than the small cymphocyte X5 MERPHOLOGY High Ni Ratio - Fine Nueleer Chromatin with 24 prominent mucleoti Presence of Auer Rudy More extortasin than Lymphoblast; (+) granules Jatelet- Moderats to sxskie firumboun topo CYTOCHEMISTRY Myeloperoxidase (MPO) Positive (+) Sudan Black B. Positive. BONE MARROW Cellularif Hypercelluler Erythropoiesis Morkedy suppressed Myelopoiesis Suppression of myeloid maturation. consisht 20% of Borte marrow Celk Mega Kngupoiesis decreased. AML prognosis- • Fulminant prognosis and has worse prognosis the ALL . (Cytogenetic morken are major determinant of prognosis.

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