University:
Camosun College
Course:
NURS132 | Promoting Health and Wellbeing
Academic year:

2023
Views:

341

Pages:

2
Author:

Aysha A

SHIGELLA Common agut Bacillary dystes// dystanice flexnen Baylii Seneii PATHOGENESIS Mode of transmission Ingestion throud cont. Fingers, food, water, flies. min effective dose 10-100 Bacilli Entry via M cells Bacilli enti mucosa via M cells and are then engulfed by macrophages insubreg, macrophages S Recrut releas baulll which induce inflammat response / cells inf site & releag cytokines Acute colitis (Hallmark) ✓ Divel cell to cell-spread //..by inducing action polymerization Fenterotoxin SHET cholera toxin -Shiga toxin 60s Ribosome. Local vasuk damaje to kidney, Brain/ Endotoxin b grame Endotoxin & induce intestinal inflammatin 2 ukeratin // CINICAL MANIFESTATIONS 1. Incubatia Period 1-4 days/ 2. Initial Phase = Walks diorhoes + fever tomalaiset Anorexia + vomitting 3. Thase of dysentery frequent passage of bloody Mucopurulent Stool with increased tenesmus and abdominal cramps Endoscopy Edenators & Hemorshagic mucosa// with ulcerations 4. Phase of complication (>5ys old) Intestinal complications = toxic mege wlon, perforations & Rectal Prolapse Metabolic- Hypoglycemia, hop. natremia, denydration. 5. Postinfectious phase: Palents exp HLA-B27, dev. (AI reaction) months after chiyellosis, charade & arthritis inflammation & urethritis. occular CAR PIAGNOSIS SPECIMEN Freon stool Transport medium- Sachs buffered glycoral saline // STOOL MICROSC •Wel mount preparatin-lore no ot pes colls, macrophers, & erothrastes// Enrichment CULTURE Enrichment broth Selenile F broty, tetrathionate broth to inhibit commensals im Selective media Selective Media Mackay agorranslucent, Nien-lactose Ferment colon! DCA (Deoxycholate Agas) Colourler NLF Colonies CULTURE SMEAR & TILID TESTING short, Grem negative, Bacilli Won-motile, Non-capsulated, nm-sporins Identificatia VITEK. Biochemicel Catalase (+) ICUT - Indole test (-), Citrate test (-), urease (-), TSI All ore Mannitol fermentors// alkaline laud sorotipins (Biochemic Voriations) Slide Aggluthatin with poly valent antisera (genus specific) gop specific antisara # Colicin typing→5. sonnei lone • Mimicrobial Susrephthis resting o Mueller Hinton ager by disk diffusion test. Ab CIPROFLOXALIN (G3 days SORSLE Dehydrations)