Influenza virus | Camosun College - Edubirdie

University:
Camosun College
Course:
NURS132 | Promoting Health and Wellbeing
Academic year:

2023
Views:

60

Pages:

3
Author:

Aysha A

INFLUENZAE Influenzae viruu Negative sense ssRNA segment segmented Influenzae-A-8 C-7 Structure Triangules Hemagglutinin More abundant -Neuraminiduse attachment of virus to cells. (sialic acid Re on Resp cells/RBC) -Matrix prot Mi M2 Less Mushroom shapel Release of vils. H ML Balay the enveble Maintains structural integrity M2 Jess in numer - lon channel Uncoating of virion in the host cell. ind uncoatiry Endocome RNA (low pH) Ve sonse) recepter (Endog losis RNA pofran (+) RNA → New copies Kelease are Formel ELUTION GROUP SPECIFIC TYPING INF VIR A Humans + Anemals Antigenic shift Epidemic & Pandemic basel H&N H: 16 types Nglot INF VIR B Humans Non-pathogenic No-antigenic Shift Seasonal Flu CIR Type A-HINH H3N2 ANTIGENIC SHIFT sudden change Exchange of RNA Segments blw influenzae A Genefic Ressortment ANTI GENIC DRIFT Gradual change Mutation in H & N Mutated Hor N CLINICAL FEATURES Incubation Period = 18-72645 Reservoir Animals, Birds Humane orever, Headache o sore throat cough Myalgia • RUNNING NOSE IS USUALLY ABSENT LAB • cpecimen Nasopharyngeal swab swab with dacron of polyester tips should be used stored in UTM (viral transport media) Upto to 4 days refrigrata at 4°C (for more days-70°c) Isolation • Amniot covif of embryonat egg. Primary Monkey kidney cell line. -eshow Hemadsorption •Antige detection -DIF • Antibay detection - HAI EUSA RT-PLR •Real time-PCP Y pained sera, drample 10-14 days apost 14-↑ in Ab significent Hemo agglutination Inhib thien test (Ab) Treatmet TAMIFLU/oseltemin-ORY Zanamivir Inhalatia Amantadine Rimanto dine for INFA NA inhibity

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