University:
Camosun College
Course:
NURS132 | Promoting Health and Wellbeing
Academic year:

2023
Views:

134

Pages:

3
Author:

Aysha A

HAEMOPHILUS INFLUENZAE factor X & V) Hemin (NAP) Oxidase (+) Gram gegative bacill VIRULENE FACTORS CAPSULAR POLYSACCHARIDE Inhibit Phagoustosis Bacterial endotoxin, Ig A1 Profenses, oute-membrane protein SEROTYPING (a to F). Some lack capsule CLINICAL MANIFESTATIONS influenzae type B is the most common and most invasive serotype of H. influenzae. ONS cause pyogenic meningitis subdural effusion. Epiglottis Cellulitis of epiglothes and supraglottic tissue Airway obstruction • Community acquired Bacterial pneumonia: Hib more common in infants, pleural involvement is more common. • Parameningeal focus (sinusitis & Otitis) meningitis Bacter Heb & non-typeable Hemophilus straine Featres Capsule pe 6 strains Poly ribosol (PRP) ribitol prosphate Nm-typeakle Non-capsulated Manifestations Invasivo = meningitis epiglothis, preumonia, bacteremia Commonly affect children Hematogenous spread Spread Hib vaccine is availalle Non-invasive- otitis media (in children) & perunonica (in adults) Adults Contagious sprend Not available Vaccine Host: Auman pathogen Mode of transmission Drop Inhalation or contact with secretions Age children <5 years of age Adulls >65 years Risk Factors Household contact, day care contre, socio-economic confitions LAB DIAGNOSIS I SPECIMEN sputum, blood, OSF > Processed immediater, should never be refrigerated Direct examination > Pleamorphic gram negative coccobacill > Capsule detection: By Quellung reaction > Antigen detection Bo lattex agglutinatin test, direct-IF or ELISA D CULTURE -Boud agar with s-aurens streak line strus satellitism // Grows well on charlak agery Fildes agor, kuninals agar. solation of H. influr // 100 Typing methods such as biotypig and serotyping (using specific antiseru) Identificatia Biochemical lest such as disk-Fest for X and V facty Automated suplems such as MALDI-TOF VITER • Molecules methods - Multiplex PCR (Biotine Filmarray), detecting common agents of pyogenic meningitis in CSF Antimicrobial susptibilit testig Hib vaccine PRP (Poribar) vibitol phosphate) = usel for vaccination Combination with DPT, Hepatitis 13 (pentavalent vacuine) at 6, 10, 14 weeks of Births ↳ IM Route, Anterolateral side of mid-thigh protection 2 or 3 docu ORAL RIFAMPIN Drug of chile