Bascillus Group - Lecture Note

BACILLUS Bacillus antacids- morphology geam tue bacilli -Pron motile -Capsulated Space forming fovale central in positan -Aerobic & facoltative anerokes. In cultacer bacilli are alleged ondt allang d ind in long choung, ends and truncate a fhen! concave Have a swollen appearance, this que bamboo stick realm •Pathogenesis mostly cattle & sheep Sovece of infections elected. disc heavy study from mouth, nose Spordale in animal number of bacilli Beecturo each soil acts as SOI mode transmission!- Breathing, spacer, eating food/devoting king watep that is containing with spaces entry & spores though Cot io skin. Virulence factors!- () Capsules polypeptide-inhibitors ( phagocytosis Anax toxo- Edema facta I -Protective antigon foctor II Lethal factor - Indivitually nos toxic. Classmate Palhompresse Dafs Page Usually septicemic bot Sometimes localized -Zoonotic disease. Human Antheax' 20 infection liem diseased animals. leads to septicemia + meangitis. d -3tynes. (1) Cutaneous and hork Ha (2) Mmonary anthrax (8) Intestinal anthrax (i) Cutaneous anthrax entry of spores through beaded skin. Affected ollies Pare, neck, back Bhas commonly seen is formers & people handling carcasses lesion 5 Malignant pestle acute inflammatory ted ا congestion with de @edem- alla Ideal necvedic lesion covered by black eschas. -may lesolve spontaneasly but Sometime leads to foetal speticema meanpitos. 2) Pulmonary anthics:- (2m) .: inhalaten of dest of filament if wool dam infected animals. in woof factories. -Also called wool soles ildect (NS-mcampinga Intestinal antheox (lace)(2m) fandin thuce who consume improperly cooked infected inaat -Bloody diauha -Highly fatal Clinical manifestation! Incubation pd:- Cutaneous-Iday Plmundry-1-day. Symptoms:- flere-like symptoms thigh kue mild chest discomfort. Complication:- Suppticomat meningitis LAB DIAGNOSIS!- Specimen collection- Soobs, fluid of pus leom pustules. Sputum and blad Gom pulmonary & septic mal anthrax micro examination:- yam staining-clam tue with large geam hans large India ink-capsule. clebt halo Pleas Tarand ballium. and Colture media Achae vel erstics:- Highly fastidious. - drobic & facultaline anceche -Temp for growth 12-15°C (opt 35-37°c) (a) Nullient afaf median 2-3 mm diameter Colones, existed Opaque & greyish while -medusa hedd appeaune. (6) Blood agar medium -Colones are not haemolytic Occasionally, allow secure tha (c) Gelatin stab cultuur Gelatio is Inquified mostly the top due to acrobic enutoonel ef. gives a characteristic Inverted fie teel appeal (d) Selective modum!- +PLET medium containing heart apar with infusion afar Pulyhyst lysoson EDTA & Thallus deetde. (e) Sodid mecum contationf penicillis:- -B antheac is grows medium ke 00 this occurs 10 chasing on the suefore I agal Shing of credits. reselling a -Useful to uff blow Ban theac Bettus celus. Bixhem exni- palucade, maltare suceare aut -fumunted with peodn & enly Calalade 15 A formed niteade In nitrites Seeulogy "Ascoli's Themoperipidis test" Treatment Doxycycline Penicillin - Ciprofloxacin Erytheo micro •Prophylaxiss- general prophylaxis- Improvement of factory hygienic pepper sterilization of animal pats like wool. Vaccine:- Sterne-animal -Hon precipitated toxid- human Bacillus cereus Causes food id pairoing. widely divlechod in nature in soil, vegetable, milk, celled, Spices, meall, paltry is service duty → few spots su Cocking & gemnale into vegetative bacilli thus causing food Poroing.