University:
Campbell University
Course:
BIOL 342 | Genetics
Academic year:

2024
Views:

288

Pages:

2
Author:

Warren Barber

Amoeba Sisters I Video Recap NAME: Amoeba Sisters Video : Mutations (Updated ) . 1 What is a mutation? f1*£L A " rvu C jju C- fl ( J A . Mutations can be harmful, helpful, or neutral in their effect. A silent mutation tends to have a neutral effect as it does not result in coding for a different amino acid Using your mRNA codon chart, give another mRNA codon that this CUU could mutate to and still code for leucine. ( \ ) f\ . 2 . A specific part of a nucleic acid (such as DNA or RNA ) experiences a mutation that could lead to a different protein produced. View the illustration below of DNA . Which part of the DNA experiences the mutation? ruAro 3. On the DNA illustration, draw an arrow to show where the answer to # 2 could be located. ^ 4. The mRNA codon CUU could mutate cue and still code for leucine, which would not change the amino acid. to WHAT?! 'This is HOT the proteinI ordered! Sw 5. Which type ( s ) of organism(s) can experience a mutation? Mark any that apply. Dude. It'sT ^ because your f * Leucine 6. Even a gene mutation that is a point mutation, meaning it affects one nucleotide base, can still make a major change Consider the below information for normal hemoglobin: Animals (this includes humans) \ / ^ 4 Archaea portion OF Bacteria HeM°8l-0blN DIM urn Fungi Afld$ Plants Protists 66A CTC CTC CCU GAG GAG Prvftie-filirtamic Aoid-Gkrtamfc Acid Sickle Cell Anemia is caused by a point mutation known as a substitution. Show what would occur if the first ! ("thymine") DNA base in the portion shown above experienced a mutation with a substitution of A ("adenine"). Sickle Cell Hemoglobin: Portion of mutated hemoglobin DNA: mRNA: Amino Acids: ProfW- ~ ©All rights reserved , C C- V CJj & h Ab (57 / yf tA^Tc l J all * §»Amoeba Sisters LLC WgpF kfift CAC CTC Amoeba Sisters I Video Recap NAME-' Amoeba Sisters Video Recap: Mutations (Updated ) 7. An insertion or deletion can result in a frameshift 8. Check your understanding! Mark any that are correct . mutation. To demonstrate this, complete the following Note: You will need o codon chart GCA mRNA: C (,0 Amino Acids : Mutations are mostly beneficial and useful for an Normal Strand: ATG DNA: UftC . Mutations are random . CAC organism kOCi A^aCTTVM INa_ ~ I a SMutations can occur in both DNA and RNA, which are \* 4 / VJCTAJL nucleic acids. Mutations can only occur during interphase . Deletion (causing a frameshift): Taking out the first "G" in the original DNA above results in: DNA: mRNA: CAA Amino Acids: AC TGC i\ CJp £tUU ) > k Q CKU ds Not all genes are "turned on" at a given Substitution mutations typically result in a frameshift mutation. ~ How did the frameshift change the amino acids ? CK <^ \ time. uk TK rt_or\ TlN 3 Not all genes code for proteins. LILSS. Mutations can be genetically inherited. Sketch It! Create illustrations to show the following chromosome mutations. Note: Chromosomes exist in both prokaryotic and eukaryotic cells, but prokaryotic chromosome structure tends to be very different from eukaryotic chromosomes 10. Deletion 9. Duplication . I n 11. Inversion 12. Translocation Amoeba Sisters LLC M r# © All rights- reserved

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