University:
University of Alberta
Course:
MMI 133 | Medical Microbiology for Health Care Professionals
Academic year:

2024
Views:

62

Pages:

2
Author:

Ali O

Entamoeba histolytica (EH) Amoebic dysentery Primary food - RBC Causes ulcers and bloody and watery diarrhea Cyst form has high resistance to Chloride Has both forms (cyst and tropzohite) Giardia lamblia (GL) Flagella Causes beaver fever and giardiasis, Flatulence (bad gas), mucousy diarrhea, nausea and cramps Cyst has high resistance to chloride Had both forms Trichomonas vaginalis (TV) Flagella NO CYST In vagina and male urethra Cause intense itching and inflammation Sexual transmission Acanthamoeba SP Grows in water Important for contact wearers Eye loss is possible Had both forms Cryptosporidium parvum (CP) Animals (rats, dogs, cows) to us Chronic diarrhea, can last forever in immunocompromised Severe even in immunocompetent ZN stain needed Oocyst has high resistance to chloride Toxoplasma gondii (TG) Life cycle in cats Acquired from undercooked meat (tissue cyst) or cat feces (oocyst) Serious for fetus Trypanosoma Blood parasites, transmitted through vectors 1. T. brucei gambiense/rhodesiense -causes african sleeping sickness (tsetse fly) 2. T. cruzi -causes Chaga's disease (reduviid/kissing bug) Leishmania Transmitted by sand fly vector Visceral (most severe), mucocutaneous, cutaneous (hard to treat, lease severe) Live and develop in macrophages Plasmodium Cause Malaria (hemolysis of RBC) - No vaccine Apicomplexa parasites - can change host cell 4 types - transmitted by Anopheles mosquito (bites at night) ↳ P. falciparum (most dangerous) - affect all ages of RBC ↳ P. malariae ↳ P. ovale ↳ P. Vivax Sporozite in saliva of mosquito and focus of infection is in liver Symptoms of falciparum malaria Fever and chills PfEMP1 (protein and virulence factor) causes sticky collections of parasites and RBC (leads to organ death) Severe consequences of P. falciparum malaria ↳ cerebral malaria: clumping and occlusion of blood vessels, also Vasculitis ↳ anemia: caused by lysis of RBC ↳ kidney failure: caused by high levels of hemoglobin breakdown products