University:
University of Alberta
Course:
MMI 133 | Medical Microbiology for Health Care Professionals
Academic year:

2024
Views:

390

Pages:

2
Author:

Ali O

Yeasts Candida Albicans · may attack to epithelial cells as a yeast, but invades deeper tissues by using pseudohyphae · C. Albicans is normal flora in the gut and mouth · can lead to candidiasis and thrush in newborns and immunocompromised Saccharomyces · yeast that's used for baking, wine, leavening dough · nonpathogenic Cryptococcus neoformans · produces a polysaccharide capsule · can cause meningitis in immunocompromised Thermally Dimorphic Fungi · can grow as a mold or yeast based on temperature ↳ mold 20* C, yeast 37* C · dimorphism: temperature dependent · the molds are considered pathogenic · dimorphic fungi are NOT infections from one person to another Mold form is spread by spores in the air Sporothrix (subcutaneous infection) Dimorphic · "Rose Gardener's Disease" · Fungal spores introduced into wound after trauma (pricked by rose thorn) · Lymphangitis: inflammation of the walls of lymphatic vessels Mycoses (Fungal Diseases) 1. Superficial Mycoses · Fungal infection along surface of hair shafts and outer layer of skin · mild infections ↳ black and white piedra (hairs of scalp) ↳ Malassezia furfur: causes discoloration 2. Cutaneous Mycoses · Fungal infection of deeper layers of the epidermis ↳ eg. ) athletes foot, ringworm · caused by dermatophytes that degrade and use keratin as a carbon source · 3 different molds with same method of pathogenicity · clinical diseases are called "tineas" 3. Systemic Mycoses · Infections in deep tissues (organs) · caused by primary pathogens such as dimorphic fungi OR opportunistic pathogens ↳ Candida albicans (the yeast listed above) ↳ Aspergillus species (causes aspergillosis when spore gets pushed into tissues)