Pedigree Analysis Problems

Pedigree Analysis Problems AP Biology Aa A Nae.Key 11 1 Ka IV 1 A Aa42 3 4 5 aa aa aa 2 3 4 5 8 10 11 12 aa Aa Aa aa aa aa aa Aa aa Aa aa 1 3 4 6 7 8 10 aa Aa aa aa Aa aa Aa Aa aa Fill in the pedigree above as completely as possible. Is the trait in question most likely autosomal recessive, autosomal dominant or X- linked? Autosomal Dominaut What is the probability that Individual 1-1 and 1-2 would have an offspring that displays the trait in question? (Show Punnt square osupor your ansmel Aa * Aa A AA Aa aa 75% would display trait What is the probability that Individual IV-10 would have an offspring with the trait in question if she mated with a male that did not display the trait? (Show Punnett square to support your answer) aa x aa a aa 0% chane offspring would display trait I 1 2 II ya y III 1 IV 2 XX 3 xaY 1 1 2 3 4 5 YAY 5 ya 6 XY xy6 7 8 Yay XX- XAY Fill in the pedigree above as completely as possible. Is the trait in question most likely autosomal recessive, autosomal dominant or X- linked? X-linked recessive What is the genotype of individual l-1? 1-2? II-1? II-2? What are the possible offspring of Individuals II-4 and II-5? What is the probability of having each possible offspring? (Show Punnett square to support your answer) I-1=XY H-4 × F-5 I-2= X^X- Parental Genatypes Pesild Gametes I-1=X^Y #-2=X*ya XAYx XAya X XX xAxa 50% of femabes "normal" 50% of females carriers 50% of mates "normal" 50% of mates affected ④ XY xay aå A 1 aa 2 A Aa 8 Aa 3 Aa aa A 10 aa 11 aa 12 ta 13 aa 14 Aa 15 A 16 A 17 aa 18 aa 19 aa Fill in the pedigree above as completely as possible. Is the trait in question most likely autosomal recessive, autosomal dominant or X- linked? Autosomal recessive What is the probability that Individual 8 and 9 would have an offspring that displays the trait in question? (Show Punnett square to support your answer) Aa x Aa A@ A AA Aa 25% would dispay the trait aa x Aa aAа What is the probability that Individual 5 and 6 would have an offspring that displays the trait in question?? (Show Punnett square to support your answer) aa A 50% would disdaya the trait Aa aa What is the probability that Individual 10 and 11 would have an offspring that displays the trait in question?? (Show Punnett square to support your answer) ad x aa a 100% would displaythe trait a aa Construction and use of a Pedigree You are a genetic counselor who has been given the following information from which your will construct a pedigree: 1. Your data: Henry has a double row of eyelashes, which is a dominant trait. Both his maternal grandfather and his mother have double eyelashes. Their spouses are normal. Henry is married to Isabella who also has normal lashes and their first child Polly has normal eyelashes. The couple wants to know the chances of any future child having a double row of eyelashes. 2. Construct two blank pedigrees. Begin with the maternal grandfather and grandmother and end with Polly. a. Pedigree 1: Try out a pattern of autosomal dominant inheritance by assigning appropriate genotypes for an autosomal dominant pattern of inheritance to each person in this pedigree. b. Pedigree 2: Try out a pattern of X-linked dominant inheritance by assigning appropriate genotypes for this pattern of inheritance to each person in your pedigree. Pedigree 1 Pedigree 2 A- aa Aa aa Henry Isabella Aa Polly aa XAY XY ISabella Henry Xy not possible Polly XX 3. Which of the Pedigrees above is correct? Pedigree 1 4. How do you know (cite specific evidence from your pedigree)? If the trait was X-linked dominaut, Polly would have to get an X chromosome from her dad, and would have doudle egelashes 5. What is your key for this trait? A = doubo eyelashes aa=normal eyelashes 6. What is the genotypeof Henry Aa and Isabella? aa 7. What garnetes can eacho tem make? A (a 8. What is the probability of Henry and Isabella having a child with double eyelashes (Show the Punnett square for evidence)? A a) a Aa aa 50% chance that offispring will have doule eye lashes