University:
Williams College
Course:
BIOL 202 | Genetics
Academic year:

2024
Views:

149

Pages:

4
Author:

f3le2i5ogc

/ DNA Mutations Practice Worksheet DIRECTIONS: Transcribe and translate the original DNA sequence. Then, do the same for each mutated DNA sequence. Then, determine the consequence, if any, for each mutation, by circling your choice for each question. You will need a Genetic Code Chart. Original DNA sequence: TAC ACC TTG GCG ACG ACT mRNA transcript: A1G UGG A AC CGC UGC UGA amino acids: met - Top - Asm-Arg - Cys- Mutated DNA sequence #1: mRNA (Circle any changes) TAC ATC TTG GCG ACG ACT AVG WAG AACCECUGGUGA Type of mutation (Circle one.) amino acids: mit- Point Substitution How did the mutation affect the amino acid sequence (protein)? (Circle one.) Frameshift Insertion or Deletion No change 1 amino acid changed Premature stop signal No stop signal 1 amino acid added/ deleted All the amino acids changed after the point of mutation Mutated DNA TAC GAC CTT GGC GAC GAC T sequence #2: mRNA transcript: GAA CCE CUG CUG A amino acids: met lav-Glu - Pro-Lev - LEU- Type of mutation (Circle one.) How did the mutation affect the amino acid sequence (protein)? (Circle one.) Point 4 Frameshift Substitution Insertion or Deletion 1 amino acid changed No change Premature stop signal No stop signal 1 amino acid added/ deleted All the amino acids changed after the point of mutation