Medicine Lecture Note: Pneumoconiosis - Edubirdie

University:
Coventry University
Course:
B940 | Biomedical Science
Academic year:

2023
Views:

378

Pages:

2
Author:

Badusha S.

Pheumo conioses →defined as lung diseases pendered by ongoric as yoully as inergenic particulbhs and chemical fumus & vapor. Pathogeness → development of Phums commoss depends on: - Amount of dust butained in the long & Airways one of dust durton of expame, effereny of host clearance prechonising) in ais 4 dize, shape & looking apocity of particles, (most dangeran parkle range in size Solubility & physiocherial Meschuity of the particle Shuller peutell soleble, deuch toxic levels & produce aute buy injury. Lerger poubels hot soluble, persets within long pearanchya for years produr phermoconieres. →pareribyul Cry disean assaicked with inhalelor of Cryshelline silicon dionde (silica) → most premtent davly progressive premo conicons & present after many year of exposure. Potho goneis susceptible individuals Sand blashes, Stor cutting, polishing & Sharpening of whls. Pathogenes inhabitas of silica pambilis (commonly quands Ayshith) reaches the alveoli & interenet with alveder alveder epithelial cells. ingested by alveoles mo bropheges Acthuck nocrophages to release medietas C12-1, TNF, fibronen &, Ros) ↓ Stimible fibroblast protitation & Stian Collegen →tchesonic silicosis two forms simple hodulas silicon progressive mession Fibras. Y Simple Modular silicon → represents early stage →Shows tiny, bandy palpable, discente silicone hodules. →hiley lymph nodes huay be enlarged. → periphery of lymph brades show thin beim of calcification. (eggshell cole ficaton)

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