Heart Failure - Lecture Note

Heart failure → defined as the pethophysiologic condition in which heart is unable to ejel blood deliverd do il by venous system. → Couns inadequat perferries of tissues or incercand diastolic fitting precesser of the loft ventricle Commen Coronary heart disean → hypertension (HTN) Types of heart Solun Depepery on Ousel chaow heart failure • greeded denlopend of head frileum. →e.g valuula beat disease by perdson, IHO → Acute head failure sudden deuclophus of heart failur eig renk byocerated infperator & rupte of Cardice valve.. Depending on alped • dysbal dysfunter with low ejection lechon. furul in peragensive detecost in of Lyocardies catrch funchon → characterised by decrean in ejector fraction > various د Cours of bredene GF aue isidemic injury, inedequate adoptelin to pression or volume ovaled due to hypertension a valentes diseas with preserved ejecten fection → inability of the hear to adequally relax & All.. → result from inchlily of heart chember to spend & All suffjarty during diastole. Cecebes massive beff rentriculer bypaleaply anyacendil Abors Constrictius pars candie Pathophysiology fardian wirkleed inuous Cardas funton compromised. → Hence Cus compensaths da for reduced myocardid contenlly A increand forestito hackens hemodynamic burden through sword honestte beherans 1. Freonk pthauling wichomim → larger volen of blood into withicle ↓ invward steakthing of Cardice byak ber prodine diletion of walls of heaw genter expension during dagslede لى Shwlched hys her intered mou forcibly increm Co. ↓ Sleges compensated heart failur → decompenseld head failur 2. Actution of neves humal systems Akuchen of ergiadasin aldobro systems. Release of albad neticente peptid. Cto balance RAAS) 3. Myocardial stenchoul adeptters. Sustained incuar in sectorial work der to pressure a volu overload → Carens hyouter hyperkupty inewens size & wagh of heart. y Pressen overload Lypertrophy → sem in chromic hypotension on veluulen Aunosis → results in concentric typanduply (ventricular well thickness incans withact in crean in size & the chamber) • Volum ouchard Lypertrophy → Seen in voluntas regurgitches New Sarcopare als adeted in series. length of husd kiber. consegluntly ventricle diletes -thickness my be inervased, horul a decomand Functioned charges Cardiac hypertrophy assocached with increw in caygın consumption by heart. →herve hypateophied Land in seseptible to ischemia. Lep sided head faleme in lell onded hostet laser left ventricle connat efferently ejel blood in the aula Cacus blood to beckup in the Cungs (produing puhunang congestan ledene). + Ekologiy Y Ischemic Law diseas Systemic Hypertension 4 Mideal arte velvulas disea + disses of byocardım Cloneul horpholog, efful are a consegure of Partive congestion "Inadigute Systemic perfun leading to organ dyshunter. 4down of blood in left sided chembors. guas depends on undedyry disean procen rupom be Left verdurch escully hypotrophical & con to dileted. →Left ventricules dilator wy & diletan of lef) astrin leed to wideal insuffering heicroscopy consist of hypadmaphy of hyouze → varicl degen of interstitied Abrais. Lungs geros due to pulmonary congushen & edene Lungs berone → heavy & boggy. → exude sus thy pink tansudele, on cut sefer. micko xopy 4 progressive edens of alveder septe. - accumulates of eden fluid in abedas speces. * in cheon haut failure Lemmesiderin leden abesla macrophages 4 are seen (hood Podle cells). Right hoaul Sales → inability of the right ventricle to effectively pump venous Lood into the lungs. Right heart files is usually the consequence of HHF. hence all stickel factors Cousing LTF is reesponsible SRHF. Com pulaconche -isoleed RHF i tuke e develops in assouton with // variety of disordes of the lungs. Inca pulmonale, kyocardial hypradorky & dilhas gestriched & Confined to sight ventricle & cdrom.