University:
Hallmark University
Course:
BIOL2420 | Microbiology
Academic year:

2023
Views:

163

Pages:

8
Author:

InterstellarIllusionist

Imunity Immune System: Body defense mechanim against infection Basic Clinical Innate 1ot Line Immunity of dense aquired Immunity -pre-exist mechanism (innate)) -aquired radaptive - non-specific ex MO against any Type of mo Specific & diversity 1st hours or days after infection (immediate) each Tcell for Specific Ag - a week after infection. have no memory - have momory Cells for Component of physical barriers & chemicadon (seretions) phagocytic Cells Indry Immune Response →Serum proteins Complements & inflamatory mediators -Component Cellular (T&B lymphocyte) Dadaptive chumeral AB & Complementy -Self Tolerance non-Seff Reacting Response is adaptive changes Response is fixed Componant of Immunity innate immunity Aphysical/Mechanical borris & prouent atuchment & Antration intact Skin-Cilia_mucus_Cilia - Cough Sorcing - Flushing actions urine, Saliva, tears, vomiting & diarrhea B Chemical barriers -Lysozyme in tears cleare B(1-9) glycosidic bond of peptidoglycan in Bart C.W interferon produced by viral infected Cell eantivirals - Complement Serum proteins activated & damag C.M of pathogen & opsonize them -Defensins Anti-microbial, chemotactic peptides impin early Protection to RS RGIT. expresand in Epth Cels & laukagte B phagocytic Cells (Macrophage MP, Natural killer cells NK cells monocytes, dendretic Cells) amp 000 Phagolysome intracellular Distruction. D inflamatory barrier or inflamation A Cellular Immunity (Cell mediated) -T-lymphocytes T-helper Specific for the Ag T-lym T-Supressor T-Cytotoxic Cytolkine memory Cell IL.2,ILY ILS INGY Plasma イム →→ anti bodies binds e Ag that Stimulate there production B-Cell memor Cells humeral immunity (AB mediated Immunity) -B-lymphocytes plasma Cell Immunoglobulin. Antibodies IgA, IgM, IgG, IgA IgD Neuralizing Ag Activate T-cytotoxic & mo Activate Complement Syst Notesop Classic Pathway Complement serum proteinsy inactivated -alternative Bart Capsules ②alternative zag Pathway @mannose-lectin Pathway activated ①→ adaptive immunity. ②③innat immunity pathway -mannose- lectin pathway Cellula component innatenunity Complement system Phagocytes classriway Pathway Antigen presenting adaptive ty immunity Antigen presenting Cells 80 phagocytes Tuprolifation ex- tendretic Cells ¯ophages Aquired Immunity Cellular Immunity Flymphocytes) Humeral Immunity (B-cells &AB Aquired Immunity I mode of development Active Immunity Passive Immunity m.o A13 B-call -The host produces Cells & AB in Response to a pathogen -long lived Immunity - The host Receives a preformed Antibodies & or immunoreactive lymphocytes - Short lived Immunity Major Cell ☆ Types That involved in immune & inflamatory Response: T-helpen Cytokines B-cells #failure of immune System T-cell- T-Cytotoxi + Tumer Cells Viral Infected Celli - immune defiency disease cinefective immune Responsen - Autoimmune disease! adaptive Immunity B-lymphocytes Th CD4 →plasma inappropriate reaction of Self Antigen - Hypersensetity reactions over active immune Responsi dendretic APC Macrophages phagocytosis + APC + Tissue repair Neutrophils phagocytosis & killing of microbes