Pharmacology
1-Phosphodiesterase that causes complications with nitroglycerine vasodilators:
a. Sildenafil
2-Thiazolide duritics action after 3-4 weeks:
a. decrease vascular resistance
3-Central acting hypertensive drug safe in pregnancy:
a. alpha methyl dopa
4-Used in heart failure but doesn't increase cardiac output:
a. duiretics
5-Antihypertensive drug given only IV and in emergencies:
a. sodium nitroprusside 6-Vasodilators not effective alone as antihypertensive:
a. reflex tachycardia and vasoconstriction
7-Effect of vasodilator in acute ischemic myocardial :
a. direct effect on coronary artery
8-Nitroglycerine administered ligually:
a. faster effect
9-Causes vasodilation in arteriole and venules
a.
Nitroprusside
10-True about Esmolol:
a. a very short duration of action
11-Has of first-dose syncope as a side effect:
a. Doxazosin
12-The reason behind which we use angiotensin 2 receptor antagonist is:
a.
It completely blocks the angiotensin II
13-A b-blocker that have short half-life and used for intraoperative and postoperative
hypertension?
a. esmolol
14-A side effect that distinguishes ACEi from ABRs?
a. Cough
b. hypotension
c. hyperkalemia
15-ARBs instead of ACEi because of
a. cough
16-Apatient with HF and suffer edema, which is the best to decrease his edema: a. furosemide
17-Ture statement:
a. low doses of thiazide have the same antihypertensive effect as high doses of it
18-In acute episodes of angina, sublingual dose of nitroglycerin is used to relief the pain
a. to ensure complete and rapid bioavailability
19-Main action of nitroglycerin in the treatment of CHF
a. reduction of venous pressure
20-A drug that has the ability to increase renal blood flow
a. Methyldopa
21-A drug that can cause angioedema in some patients
a. Lisinopril
22-A drug that is prescribed for diabetic patients even those who don’t have HT
a. Lisinopril
23-A drug that causes headache, flushing, and ankle edema
a. Nifedepine
24-This drug causes Lupus like syndrome with high doses
a.
b.
c.
d.
e.
Hydralazine
Minoxidil
Diltiazem
Sodium nitroprusside
Diazoxide
25-Which of the following beta blockers is B1 selective and has nitric oxide potentiating
vasodilatory effects
a. Esmolol
b. Carvedilol c. Labetalol
d. Nebivolol
e. Atenolol
26-After 6-8 weeks of use, the main mechanism for the antihypertensive effect of thiazide
diuretics is
a.
b.
c.
d.
e.
Reduction of blood volume
Reduction of peripheral vascular resistance
Reduction of sympathetic nerve activity
Inhibition of aldosterone secretion
Inhibition of angiotensin II production
27-Unique about ACEi:
a. it’s ability to inhibit the enzyme, so decreasing angiotensin 2
Answers:
1
2
3
4
5
6
a
a
a
a
a
a
7
8
9
10
11
12
a
a
a
a
a
a
13
14
15
16
17
18
a
a
a
a
a
a
19
20
21
22
23
24
a
a
a
a
a
a
25
26
27
d
b
a
Pharmacology Test Answer Key
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