17/01/22 ANTIVIRAL DRUGS. SYNOPSIS * How vines enters the cell. * HIV- classer of deugs fusion R.T integrareProteace * furcion R CD4 -GP 410 CCR-5. competitive → NRTI 1st hen * RTI non -11 →NNRTI 2nd Cep S/E * Hep. B (NRTI) LET. regimen * Integrate. *4 Proteare -Ritonavir Boosting Lipodystrophy syndrome Zidovudine. BM suppress Tenofovir Lamivudine min. S/E SAFEST NRTI • Sta- max. P.N - Aidan osine. → max. Acute Pancreatitis • Zalcitabine • Emtri U • Abacavir. frisk of MI NRTI also used for HBV (Hep. B) mnemonic L.E.Tà defeat H.B.V. - Lamivudine E - Emtricitabine - Tenofovir NNTRI * prove given along to RESISTANCE development others. 50 * only used HIV is againet HIV-1. intrinsically Recistant to NNRTI) * metab. by CYP. (microsomal emymes.