University:
Stanford University
Course:
MED 101 | Human Anatomy
Academic year:

2023
Views:

480

Pages:

2
Author:

larbi43100

‭Complications‬ ‭The four main complications of peptic ulcer disease (apart from‬ ‭cancerization of a GU) are:‬ ‭ emorrhage: the most frequent complication (15% of patients, especially‬ h ‭the elderly), responsible for 5 to 10% mortality; perforation: 6 to 7% of‬ ‭-‬ ‭patients (especially if elderly);‬ -‭ ‬ ‭penetration: it is a form of perforation which obstructs spontaneously‬ ‭upon contact with a nearby viscus (pancreas for UD, left hepatic lobe‬ ‭for UG);‬ ‭-‬ ‭obstruction: 1 to 2% of patients.‬ ‭-‬ ‭Additional examinations mainly include barium transit, endoscopy and‬ ‭testing for Helicobacter pylori.‬ ‭Double contrast barium transit‬‭-It most often allows you to see the ulcer (90%‬ ‭of cases), unless it is very superficial, like that created by non-steroidal anti-‬ ‭inflammatory drugs. It also provides information on the benign (radiation of the‬ ‭gastric mucosal folds from the banks of the ulcer niche) or malignant (diameter‬ ‭greater than 3 cm) nature of a gastric ulcer. However, confirmation must be‬ ‭histological.‬ ‭Endoscopy‬‭-It allows direct visualization of the lesion,‬‭the performance of‬ ‭several biopsies and the monitoring of the ulcer under treatment.‬ ‭Testing for Helicobacter pylori‬‭-The three non-invasive diagnostic‬ ‭methods (thus requiring neither endoscopy nor biopsy) are summarized in‬ ‭the table below:‬ ‭Principles‬ ‭Testing‬ ‭Breath test‬ ‭After ingestion of carbon-13 radiolabeled urea, the‬ ‭urease produced by H. pylori releases CO into the‬ ‭exhaled air.‬‭2‭r‬ adio-labeled.‬ ‭Serology‬ ‭Identification of IgG directed against H. pylori by‬ ‭ELISA test.‬ ‭Research Hp‬ ‭antigens in‬ ‭the stool‬