Introduction to Pharmacodynamics | Virginia Maryland College of Veterinary Medicine

University:
Virginia Maryland College of Veterinary Medicine
Course:
VM 8164 | The Normal Animal
Academic year:

2023
Views:

163

Pages:

1
Author:

Sarah Landeck

The therapeutic range represents ideal plasma drug concentration dosing based on ED 50 therapeutic index is TD so ED so drugs with a wide therapeutic index are safer Pharma co dynamics how drugs produce effects in the body Endogenous substances are made by the body G protein coupled receptors are where most drugs bind Ichyemalaxis acute tolerance with rapid onset Selectivity is the specificity of a drug for a type of recepto more selective drugs have stronger effects on the targe receptor and have side fewer Potency concentrations the same effect different of Competitive antagonists bind would normally bind to at a different t reversible adding site but drugs needed to induce at the same site the ligand Noncompetitive antagonists bind site and change shape of site allosteric antagonists more effects can be agonist helps easily removed from site remove reversible ant potency gonist decreases