University:
West Coast University
Course:
NURS 180 | Pharmacology
Academic year:

2022
Views:

65

Pages:

1
Author:

Isabella Bolton

ACTIVE LEARNING TEMPLATE: Medication STUDENT NAME _____________________________________ clopidogrel MEDICATION __________________________________________________________________________ REVIEW MODULE CHAPTER ___________ platelet agrregation inhibitor CATEGORY CLASS ______________________________________________________________________ PURPOSE OF MEDICATION Expected Pharmacological Action Inhibits platelet aggregation by selectively preventing the binding of adenosine diphosphate to its platelet receptor. It is an analog of ticlopidine. The drug's effect on the adenosine diphosphate receptor of a platelet is irreversible Therapeutic Use Consequently, clopidrogrel prolongs bleeding time Complications Hematologic: Thrombotic thrombocytopenic purpura, epistaxis.CNS: Headache, dizziness, depression. Respiratory: URI, dyspnea, rhinitis, bronchitis, cough.Skin: Rash, pruritus CV: Chest pain, edema, hypertension, thrombocytic purpura. GI: Abdominal pain, dyspepsia, diarrhea, nausea Contraindications/Precautions Hypersensitivity to clopidogrel; intracranial hemorrhage, peptic ulcer, or any other active pathologic bleeding Interactions Drug: NSAIDS may increase risk of bleeding events. Herbal: Feverfew, garlic, ginger, ginkgo may increase risk of bleeding. Medication Administration OralDo not administer to persons with active pathologic bleeding.Discontinue drug 7 d prior to surgery. Nursing Interventions Carefully monitor for and immediately report S&S of GI bleeding, especially when coadministered with NSAIDs, aspirin, heparin, or warfarin.Lab tests: Periodic platelet count and lipid profile.Evaluate patients with unexplained fever or infection for myelotoxicity. Client Education Evaluation of Medication Effectiveness therapeutic response: absence of stroke, MI ACTIVE LEARNING TEMPLATES Report promptly any unusual bleeding (e.g., black, tarry stools).Avoid chronic aspirin or NSAID use unless approved by physician.Do not breast feed while taking this drug. THERAPEUTIC PROCEDURE A7