University:
West Coast University
Course:
NURS 180 | Pharmacology
Academic year:

2022
Views:

231

Pages:

1
Author:

Annalise Mayer

MODULE 9: THE ENDOCRINE SYSTEM DRUG THERAPY FOR DIABETES MELLITUS Oral hypoglycemics Sulfonylureas – glipizine (Glucotrol) Meglitinides – repaglinide (Prandin) Biguanides – metformin (Glucophage) Thiazolidinediones – pioglitazone (Actos) Alpha-glucosidase inhibitors – acarbose (Precose) Gliptins – sitagliptin (Januvia) Injectable hypoglycemics Insulin – lispro (Humalog), Regular (Humulin R), insulin glargine (Lantus) NPH (Humulin N) peaks 6-14hr-> eat snake after 8hr to prevent hypoglycemia then recheck in 15 mins Amylin mimetics – pramlintide (Symlin) Incretin mimetics – exenatide (Byetta) Hyperglycemics – glucagon (GlucaGen) DRUG THERAPY FOR THYROID DISORDERS Thyroid replacements – levothyroxine (Synthroid) Expected: decrease in TSH-> Increase in T4, improve mood Antithyroid drugs Propylthiouracil – propylthiouracil (PTU)-> agranulocytosis Radioactive iodine – iodine-131 (131I, Iodotope) DRUG THERAPY FOR HYPOTHALAMIC DISORDERS Growth hormone – somatropin (Genotropin, Nutropin, Humatrope, Serostim) Antidiuretic hormone – desmopressin (DDAVP, Stimate, Minirin ) DRUG THERAPY FOR ADRENAL DISORDERS Glucocorticoids – hydrocortisone (Solu-Cortef) Mineralocorticoids – fludrocortisone (Florinef)