University:
West Coast University
Course:
NURS 180 | Pharmacology
Academic year:

2022
Views:

148

Pages:

1
Author:

Dominick Dickson

MODULE 10: THE IMMUNE SYSTEM DRUG THERAPY TO PREVENT DISEASE Childhood vaccines Adult and older adult vaccines DRUG THERAPY FOR CANCER Cytotoxic drugs Antimetabolites Folic acid analog – methotrexate Pyrimidine analog – cytarabine (Cytosar-U, DepoCyt) Purine analogs – mercaptopurine (Purinethol) Alkylating agents Nitrogen mustards – cyclophosphamide Nitrosoureas – carmustine (BiCNU) Platinum compounds – cisplatin Antitumor antibiotics Anthracyclines – doxorubicin (Adriamycin, Doxil) Antimitotics Vinca alkaloid – vincristine Taxanes – paclitaxel (Taxol, Abraxane) Topoisomerase inhibitors – topotecan (Hycamtin) Hormonal agents Gonadotropin-releasing hormone agonists – leuprolide (Lupron, Lupron Depot) Androgen receptor blockers – flutamide Estrogen receptor blockers – tamoxifen (Soltamox) Aromatase inhibitors – anastrozole (Arimidex) Monoclonal antibody – trastuzumab (Herceptin) Biologic response modifiers Interferon – interferon alfa-2a (Roferon-A), interferon alfa-2b (Intron A) Targeted antineoplastic drugs BCR-ABL tyrosine kinase inhibitor – imatinib (Gleevec) DRUG THERAPY FOR HIV Antiretrovirals Viral entry blockers Entry and infusion inhibitors – enfuvirtide (Fuzeon) CCR5 antagonist – maraviroc (Selzentry) Enzyme inhibitors Nucleoside reverse transcriptase inhibitors (NRTIs) – zidovudine (Retrovir) bone marrow suppression, agranulocytosis, aplastic anemia. Non-nucleoside reverse transcriptase inhibitors (NNRTIs) – delavirdine (Rescriptor) Integrase inhibitor – raltegravir (Isentress) Protease inhibitors (PIs) – ritonavir (Norvir)