University:
West Coast University
Course:
NURS 180 | Pharmacology
Academic year:

2022
Views:

145

Pages:

2
Author:

Prince Sampson

PROCAINAMIDE PROCHLORPERAZINE PROMETHAZINE Name/Class: PROCAINAMIDE (Pronestyl)/Antiarrhythmic Description: Procainamide prolongs ventricular repolarization, slows conduction, and decreases myocardial excitability. Indications: Ventricular fibrillation and pulseless ventricular tachycardia refractory to lidocaine. Contraindications: Hypersensitivity to procainamide or procaine, myasthenia gravis, and 2nd- or 3rd-degree heart block. Precautions: Hypotension, cardiac enlargement, CHF, AMI, ventricular dysrhythmias from digitalis, hepatic or renal impairment, electrolyte imbalance, or bronchial asthma. Dosage/Route: 20 to 30 mg/min IV drip up to 17 mg/kg to effect, then 1 to 4 mg/min. Ped: 15 mg/kg/IV/IO over 30 to 60 min. Name/Class: PROCHLORPERAZINE (Compazine)/Antiemetic Description: Prochlorperazine is a phenothiazine derivative similar to chlorpromazine with potent antiemetic properties and fewer sedative, hypotensive, and anticholinergic effects. Indications: Severe nausea and vomiting or acute psychosis. Contraindications: Hypersensitivity to phenothiazines coma or depression. Precautions: Breast cancer, children with acute illness or dehydration. Dosage/Route: 5 to 10 mg IV/IM. Ped: 0.13 mg/kg IV/IM/PR if > 10 kg or > 2 years. Name/Class: PROMETHAZINE (Phenergan)/Antiemetic Description: Promethazine is an anticholinergic agent that enhances the effects of analgesics and is a potent antiemetic. Indications: Nausea and vomiting, motion sickness, to enhance the effects of analgesics, and to induce sedation. Contraindications: Hypersensitivity to phenothiazines. Precautions: Hepatic, respiratory, or cardiac impairment, asthma, hypertension, elderly, or debilitated patients. Dosage/Route: 12.5 to 25 mg IV/IM/PR. Ped: 0.5 mg/kg IV/IM/PR.