University:
West Coast University
Course:
NURS 180 | Pharmacology
Academic year:

2022
Views:

228

Pages:

2
Author:

Prince Sampson

AMIODARONE AMRINONE AMYL NITRITE Name/Class: AMIODARONE (Cordarone, Pacerone)/Antidysrhythmic Description: Amiodarone is an antidysrhythmic that prolongs the duration of the action potential and refractory period and relaxes smooth muscles, reducing peripheral vascular resistance and increasing coronary blood flow. Indications: Life-threatening ventricular and supraventricular dysrythmias, frequently atrial fibrillation. Contraindications: Hypersensitivity, cardiogenic shock, severe sinus bradycardia, or advanced heart block. Precautions: Hepatic impairment, pregnancy, nursing mothers, children. Dosage/Route: 150 to 300 mg IV over 10 min, then 1 mg/min over next 6 hours. Ped: 5 mg/kg IV/IO, then 15 mg/kg/day. Name/Class: AMRINONE (Inocor)/Cardiac Inotrope Description: Amrinone enhances myocardial contractility, increasing output, and reduces systemic vascular resistance. Indications: To increase cardiac output in CHF or children in septic shock or myocardial dysfunction. Contraindications: Hypersensitivity to amrinone or bisulfites. Precautions: CHF immediately after MI (may cause ischemia). Dosage/Route: CHF: 0.75 mg/kg IV over 2 to 3 min, then drip at 5 to 15 mcg/kg/min titrated to hemodynamic response (may repeat bolus at 30 min). Septic shock or myocardial dysfunction in peds: 0.75 to 1 mg/kg IV over 5 min, repeated up to 2 times to 3 mg/kg, then drip of 5 to 10 mcg/min IV. Name/Class: AMYL NITRITE (Amyl Nitrite)/Vasodilator Description: Amyl nitrite is a short-acting vasodilator similar to nitroglycerin. Binds with hemoglobin to help biodegrade cyanide. Indications: Acute cyanide poisoning. Contraindications: None for acute cyanide poisoning. Precautions: None. Dosage/Route: 0.3 mL ampule/min (crushed) until sodium nitrate infusion is ready. Ped: same as adult.