University:
West Coast University
Course:
NURS 180 | Pharmacology
Academic year:

2022
Views:

436

Pages:

2
Author:

Charlee Buchanan

DIAZOXIDE DIGOXIN DIGOXIN IMMUNE FAB Name/Class: DIAZOXIDE (Hyperstat)/Antihypertensive Description: Diazoxide is a rapid-acting thiazide nondiuretic hypotensive and hyperglycemia agent that reduces BP and peripheral vascular resistance. Indications: Rapidly decreases BP in hypertensive crisis Contraindications: Hypersensitivity to thiazides, cerebral bleeding, eclampsia, significant coronary artery disease. Precautions: Diabetes, impaired cerebral or cardiac circulation, renal impairment, corticosteroid or progesterone therapy, gout, or uremia. Dosage/Route: 1 to 3 mg/kg IV up to 150 mg, repeated/5 to 15 min, as needed. Ped: same as adult. Name/Class: DIGOXIN (Digoxin, Lanoxin)/Cardiac Glycoside Description: Digoxin is a rapid-acting cardiac glycoside used in the treatment of CHF and rapid atrial dysrhythmias. It increases the force and velocity of myocardial contraction and cardiac output. It also decreases conduction through the AV node, thus decreasing heart rate. Indications: Increase cardiac output in CHF and to stabilize supraventricular tachydysrhythmias. Contraindications: Hypersensitivity, ventricular fibrillation, or ventricular tachycardia except due to CHF. Precautions: Reduce dosage if digitoxin taken within 2 weeks. Toxicity potentiated by an MI and with hypokalemia, hypocalcemia, advanced heart disease, incomplete heart block, corpulmonale, hyperthyroidism, respiratory impairment, children, elderly or debilitated patients, and hypomagnesemia. Dosage/Route: 0.25 to 0.5 mg slowly IV. Ped: 10 to 50 mcg/kg IV. Name/Class: DIGOXIN IMMUNE FAB (Digibind)/Antidote Description: Digoxin immune FAB is comprised of fragments of antibodies specific for digoxin (and effective for digitoxin) and prevents the drug from binding to receptor sites. Indications: Life-threatening digoxin or digitoxin toxicity. Contraindications: Hypersensitivity to sheep products and renal or cardiac failure. Precautions: Patients with prior sheep or bovine antibody fragments, renal impairment, and allergies. Dosage/Route: Dose dependent upon patient digoxin or digitoxin levels.