University:
West Coast University
Course:
NURS 180 | Pharmacology
Academic year:

2022
Views:

76

Pages:

2
Author:

Hallie Randolph

METOCLOPRAMIDE METOPROLOL MIDAZOLAM Name/Class: METOCLOPRAMIDE (Reglan)/Antiemetic Description: Metoclopramide is a dopamine antagonist similar to procainamide but with few antidysrhythmic or anesthetic properties. Its antiemetic properties stem from rapid gastric emptying and desensitization of the vomiting reflex. Indications: Nausea and vomiting. Contraindications: Hypersensitivity, allergy to sulfite agents, seizure disorders, pheochromocytoma, mechanical GI obstruction or perforation, and breast cancer. Precautions: CHF, hypokalemia, renal impairment, GI hemorrhage, intermittent porphyria. Dosage/Route: 10 to 20 mg IM; 10 mg slow IV (over 1 to 2 min). Ped: 1 to 2 mg/kg/dose. Name/Class: METOPROLOL (Lopressor)/Beta Blocker Description: Metroprolol is a beta-adrenergic blocking agent that reduces heart rate, cardiac output, and blood pressure. Indications: AMI. Contraindications: Cardiogenic shock, sinus bradycardia < 45, 2nd- or 3rd-degree heart block, PR interval > 0.24, cor pulmonale, asthma, or COPD. Precautions: Hypersensitivity, hepatic or renal impairment, cardiomegaly, CHF controlled by digitalis and diuretics, AV conduction defects, thyrotoxicosis, diabetes, or peripheral vascular disease. Dosage/Route: 5 mg slow IV/5 min up to 3 times. Name/Class: MIDAZOLAM (Versed)/Sedative Description: Midazolam is a short-acting benzodiazepine with CNS depressant, muscle relaxant, anticonvulsant, and anterograde amnestic effects. Indications: To induce sedation before cardioversion or intubation. Contraindications: Hypersensitivity to benzodiazepines, narrow-angle glaucoma, shock, coma, or acute alcohol intoxication. Precautions: COPD, renal impairment, CHF, elderly. Dosage/Route: 1 to 2.5 mg slow IV; 0.07 to 0.08 mg/kg IM (usually 5 mg). Ped: 0.05 to 0.2 mg/kg IV: 0.1 to 0.15 mg/kg IM; 3 mg intranasal.