Glycolysis Cellular Respiration

Glycolysis - Cellular Respiration • All 10 reactions of glycolysis to occur in cytosol • 1, 3 using ATP • 3 = regulated step • Converting DHAP to Glyceraldehyde 3-phosphate (5) ↳ allow glycolysis to proceed by one pathway • 7, 10 producing ATP • During E payoff, 4 ATP are produced for a net gain of 2ATP • glu ← 6C 2 pyruvate 3C Phosphorylated Production of ATP (Step 7 + 10) ATP substrate level phosphorylation ADP 000 Phosphorylated substrate Feedback Inhibition: enzyme in a pathway is inhibited by the product of that pathway Allosteric Enzyme phosphofructokinase (step 3) ↳ Inhibited by ↑ levels of ATP has 2 binding sites for ATP active site (enzyme - substrate binds) •regulatory site (conformational change lowers reaction rate) Start with Glucose (6C) E stored in C-H bonds glucose (glucose-6-phosphate) 1st half A potential E - using ATP (step 1+3) 2nd half - producing ATP (step 7.10) 2 pyruvate (found in cytosol Ends with transfered mitochondria), 4 ATP, & 2 NADH Cellular Respiration glycolysis (pyruvate) pyruvate processing Krebs Cycle / citric acid cycle (TCA) ETC (electron transport chain) / oxidative phosphorylation Pyruvate Processing • Reactions produce acetyl-CoA, 1 NADH. & 1 carbon is oxidized to CO₂ 2 pyruvate → 2 acetyl-CoA 2 NADH produced 2 CO₂ released