University:
York University
Course:
CHEM 2550 | Pharmacology for Health Sciences
Academic year:

2022
Views:

105

Pages:

2
Author:

Niklas

-Seizures: Characterized by abnormal electrical activity in brain. Epilepsy is chronic condition of recurrent seizures Characteristics: Depends on type -Underlying cause maybe idipathic, or provoked by stroke, injection, metabolic, drags / Frott. Anti-Seizure drugs- How do they work? 1. excitatory neurotransmite is 2.1 inhibitory neurotranam Hors. 1. Hydantoing: Phomytion 2 MOA: & excitation, enhances inhibition 3 Uses: prevent seizuresespecially tonic -tmic 4. Therapeutic Levd: 10-20mcg/ml (periodic monitoring required) 5.SE/ADR hyperglycemia, H/A, dizzy, confusion, gum hyperplasia, thrombocytopenia, leukopaina, hepatic injury, storone Jomason, syndroms, teratogenic-fetal matformation, smicidal ideation, depression. Precaution -Impairs vitamin D mdalaslism aborption of calcium ir/f Nierparatis→↑Fradures. -Do not stop noddenly status epilepticus. -Impoins foric and alosoption. 7. Admin Capsule, suspension, IV infusion; mfusion rate