University:
Auburn University
Course:
BIOL 3500 | Perspectives in Immunology
Academic year:

2019
Views:

151

Pages:

3
Author:

Rhoebi

✔ - right answer Question 3 Choose the true statements: ✔ ● ✔ ✔ Antihistamins can be effective in both allergic and pseudoallergic reactions. Pseudoallergic symptoms are never dose-dependent. lgE is involved in the development of pseudoallergy. Pseudoallergens cause direct mastcell degranulation. Question 4 Where does the central tolerance of B-cells take place? ● ● ✔ ● ● (no answer) lymphnode bone marrow spleen foetal liver Question 5 Which factor has NOT a role in pathogenesis of rheumatoid arthritis? ● ● ● ✔ ● (no answer) periodontitis predisposing genes citrullination Interferon signature Question 7 All of the following are true about type I hypersensitivity reactions, except ● ✔ ● ● ● (no answer) activates the alternative complement pathway can be mediated by autoreactive antibodies mediated by IgG or IgM not IgE the antibodies bind to the self antigen on cell membranes and extracellular matrix Question 9 Multicellular parasites evade immune system, because: ● ● ● ✔ ● (no answer) Macrophages cannot phagocytose them, so there is no antigen presentation. They have hiding color. They inhibit the fusion of the phagosome with the lysosome. They mask themselves with host proteins. Question 12 The first reaction to viral infection is: ● (no answer) ✔ NK-mediated killing of infected cells ● inflammation ● ● production of type I. interferons T cell-mediated killing of infected cells Question 13 Natural killer (NK) cells play an important role in protecting against tumors. Which of the following ● ● ✔ ● ● substances is found in the intracytoplasmic granules of NK cells? interferon gamma perforin myeloperoxidase lysozyme Question 15 The first reaction to viral infection is: ● ● ● ✔ ● (no answer) inflammation NK-mediated killing of infected cells production of type I. interferons T cell-mediated killing of infected cells Question 16 During the antitumor response: ● ● ✔ ● ● (no answer) M2 macrophages support B cell antibody production Mi2 macrophages suppress the antitumor immune response M1 macrophages are identical to N1 granulocytes M1 macrophages suppress the antitumor immune response Question 17 Chronic transplant rejection ● ✔ ● ● ● (no answer) Is a type IV hypersensitivity reactions Is a type IlI hypersensitivity reactions is a type I hypersensitivity reactions Is a type I hypersensitivity reactions Question 18 Which mediators are included in granules of mastcells ● ● ✔ ● ● (no answer) Prostaglandin Histamine IL.3 Platelet activating factor Question 21 What is characteristic for autoimmune disease? ● (no answer) ● ● ● ✔ always systemic disease more frequent in men genetic background is not part of their pathogenesis multifactorial Question 25 Which of the following is NOT true for hypersensitivity reactions ● ✔ ● ● ● (no answer) Hypersensitivity reactions are mediated by antibodies or cells. Any organ can be affected by hypersensitivity reactions. Adaptive immune system is involved. Are usually directed against non-self structures. Question 28 Which disease can be treated with anti-TNF therapy? ● ✔ ● ● ● (no answer) rheumatold arthritis erythema nodosum APECED DiGeorge syndrome

Tolerance Autoimmunity Test 1 Questions and Solutions

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