University:
Boston University
Course:
CAS CS 200 | Computer Science Workshops
Academic year:

2024
Views:

346

Pages:

3
Author:

Skye S.

Stress disrupts homeostasis, which is the maintenance of a stable environment in the body. It can be either positive (eustress) or negative (distress), and can be triggered by psychological, physical, or physiological stimuli. Chronic stress has been linked to various health issues such as diminished immunity, cancer, heart disease, and depression. Bullet points Mechanisms Of Allostatic Load Accumulation ● ● ● ● Repeated stressful experiences Inability to adapt to stress Prolonged reaction to a stressor Inadequate response to a stressor Allostatic Overload ● ● ● ● Occurs when stress exceeds the body's ability to adapt May manifest as pathophysiological disorders Lifestyle choices play a role in adaptive capacities If allostatic load is significantly reduced, the body may reestablish homeostasis Common Stress-Related Disorders ● ● ● ● ● ● ● ● ● ● Asthma Hypertension Atherosclerosis Irritable bowel syndrome Autoimmune disease Migraine headache Cardiac rhythm disturbances Peptic ulcer disease Cerebrovascular disease Skin disorders such as urticaria (hives) ACES: Adverse Childhood Experiences ● ● ● Pediatrician Dr. Nadine Burke Harris explored the effects of ACES on health status ACE reduction reliably predicts decrease in multiple conditions Long-term effects of childhood ACEs include mental health, medical treatment or pharmacotherapy, separation or divorce Magnitude of the Solution: The Deepest Well ● ● Alcohol, HIV, Heavy High-Risk Drinking, Cardiovascular Disease Anxiety, Cancer, Healing, Long-Term Effects, Hopelessness Attributable risk Mental Health Dissatisfaction Condition(s) NADINE BURKE HARRIS, M.D. ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● Disturbed 14 + Days of Work / Activity Increased blood pressure Stressor Central nervous system Increased blood glucose Hypothalamus Emotional responses to stress Immune responses Corticotropin-releasing hormone (CRH) Sympathetic nervous Posterior Anterior* system pituitary pituitary ADH/vasopressin ACTH Neuropeptide Epinephrine Y (NPY) Norepinephrine TH2O retention Adrenal cortex Blood Pupil Piloerection Bronchodilation Increased lipolysis Liver pressure dilation (goosebumps) Cortisolt Sweat gland Arteriole smooth Increased force and rate Decreased glycogen action muscle contraction of cardiac contraction synthesis Blood pressure Luteinizing Blood and cardiac (armpits and palms) hormones, levels of output estradiol, amino acids# testosterone Increased cardiac Increased Vasoconstrictor output Pancreas glycogenolysis Lipolysis Atrophy of Lipogenesis Vascular growth extremities lymphoid face and factor tissue trunk Increased circulating Decreased Increased Angiogenic free fatty acids insulin glucagon factor Anti-inflammatory Immunosuppression Decreased glucose Increased or or enhanced "Variable changes in B-endorphins, growth hormone, and prolactin uptake in skeletal gluconeogenesis proinflammatory humoral immunity1 (see text). Muscle and adipose Effects may be dependent on amount of cortisol and nature of the stressor. Caused by protein catabolism in muscle, adipose tissue, skin, bones, lymphoid tissue. ● Increased blood glucose ADH, Antidiuretic hormone; ACTH. adrenocorticotropic hormone. Mosby items and derived items e 2012 Mosby, Inc., an imprint of Elsevier Inc.