Appendix N Citric Acid Cycle | Eastern Kentucky University - Edubirdie

University:
Eastern Kentucky University
Course:
CHE 431 | Metabolic Biochemistry
Academic year:

2020
Views:

459

Pages:

1
Author:

Trevon Bernard

Appendix N: Citric Acid Cycl Citric Acid Cycle Pyruvate Dehydrogenase Complex Eukaryotes: CAC occurs in mitochondrial matrix Prokaryotes: CAC occurs in cytoplasm Step 1 Step 3 (Rate limiting step) Step 4 Reactants Products 1 Acetyl CoA 3 NAD+ 1 FAD 1 ADP 1 Pi 3 H2 O 2 CO2 3 NADH 1 FADH2 1 ATP 3 H+ Step Regulatory Enzyme 1 Citrate Synthase 3 Isocitrate dehydrogenase (Rate limiting enzyme) 4 a -Ketoglutarate dehydrogenase complex Inhibitors / Activators Inhibitors: ATP, NADH, Citrate, Succinyl-CoA Activator: ADP Inhibitors: ATP and NADH Activators: ADP and NAD+ Inhibitors: Succinyl-CoA, NADH, ATP Activator: ADP

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