University:
Hallmark University
Course:
BIOL2420 | Microbiology
Academic year:

2023
Views:

426

Pages:

3
Author:

InterstellarIllusionist

Anti-biotics Resistance black of effect of antibiotic agent against a previously Susceptible microbe. MIC MBC Antiblok minimum inhibitury Concentration = lowest Concentration of AB that growth of m.o- minimum Bactericidal Concentration lowest Concentration of AB that kills the m-o- #(AB sensitivity test) test the Resistance of AB- mo-A moB Mechanism of AB Resistance во Decreased permeability across Cell wall ↓ pure Size Efflure pumps 3 Inactivation of enzymes. B-lactamase →B-lactamase NB-lactam penicillin Ring-cephalosporin Notesap Coded #plasmid node transfered by Conjugation except S.aureus by transduction A Extended Spectrum B-adam resistance to penicillin, 2nd, 3rd G Cephalosporin & monobactam sensitive to Carbapenemse Cephamycing over come resistance by of B-lactamase Inh. (resis USR ceclavulanic acid/Sulbactam)) ESBL tresis to cephamycins AmpC B-lactame Sensitive Carbapenems Cannt over come of BL+BLInh] by use Aminoglycosides modifying Enzyme →Adenyltransferase Acetyl transferase phosphutransferase G+ G-1) Chloramphenicol Acetyltranferase Enterobacteriacea)) By modifying target Site. B-lactam AB PBP PBP-29 PBP B-lactamase Mec ) A gene Plasmid Chromosome. for PBP-29 Juse Glycopeptide AB (Vancomyci