University:
Johns Hopkins University
Course:
ME.250 | Medicine
Academic year:

2023
Views:

31

Pages:

3
Author:

5prinzg1s

1. A 45 y old female presented with proximal femoral mass associated with bone destruction, grossly the mass was glistening whitish blue, with myxoid areas. The most likely diagnosis is a. b. c. d. Ewing sarcoma Osteosarcoma Chondrosarcoma Fibrosarcoma 2. Middle aged male presented with joints pain and mass at elbow joint, aspiration revealed needle like bodies, The most likely diagnosis is: a. b. c. d. Reumatoid arthritis Hypercalcemia Suppurative arthritis Gout 3. A 40y old female of positive pregnancy test, presented with a grape like mass confined to uterine cavity, karyotyping is of diploid pattern. The most likely diagnosis is a. b. c. d. Partial hydatidiform mole Complete hydatidiform mole Twin pregnancy Invasive mole 4. Regarding vulvar Paget's disease, all of the followings are true except a. b. c. d. Representing an intra-epidermal adenocarcinoma Prognosis is determined by the state of the underlying carcinoma Most of the cases are associated with underlying carcinoma Arises from mutipotential epidermal cells 5. All of the Followings are true in in situ lobular carcinoma, Except a. b. c. d. Rarely associated with calcification Usually presented with small palpable mass Minimal atypia More than 50% are bilateral 6. All the following are true regarding the effect of hormones on mammary tissue, Except a. Pain usually occurs in proliferative (estrogen) phase b. In lactational phase, the mammary stromal density is decreased c. In menopause, fatty tissue is predominate d. Secretion is under control of progesterone 7. A 30y old patient presented with a single osteolytic long bone lesion, and this pathology has a relationship with Receptor Activator of Nuclear Factor K, the most likely diagnosis is: a. b. c. d. Giant cell tumor Aneurysmal bone cyst Paget's disease of the bone Osteoporosis 8. A 45 y old female presented with a large breast mass, that revealed leaf- like projections, all of the followings are bad histological features, Except a. b. c. d. increased mitosis Extensile growth pattern Anaplasia Stroma hypercellularity 9. In Cervical intraepithelial lesions, all of the followings are true Except a. b. c. d. Changes may be associated with koilocytosis Only 10% of LSIL will progress to carcinoma Most of HSIL will progress to carcinoma Carcinoma in situ means full thickness dysplasia 10. An ovarian tumor of solid and cystic components, histologically revealed small follicles containing an acidophilic material, The most likely diagnosis: a. b. c. d. Granulosa cell tumor Serous cystadenoma Thecoma Dermoid cyst 11. A young lady presented with bilateral nipple discharge, the least likely cause is a. b. c. d. Drugs effect Small ducts papillomas Ductal carcinoma Fibrocystic changes 12. A 50 y old female presented with an infiltrative breast mass, that showing cords of single cells arranged in lines, and associated with loss of Ecadherin expression, the most likely diagnosis is a. b. c. d. In situ ductal carcinoma Invasive lobular carcinoma In situ lobular carcinoma Invasive ductal carcinoma of tubular type 13. A 50Y old male has backache and hip joint pain, worsen at night, physical examination revealed enlarged distal pharyngeal joints with bony prominences at the vertebral bodies on X-ray. The most likely diagnosis is a. b. c. d. Gout Infectious arthritis Rheumatoid arthritis Osteoarthritis