Some Phenomena in Eukaryotes | Study Guide - Edubirdie

University:
Kentucky State University
Course:
BIO 408 | Cell Biology
Academic year:

2019
Views:

425

Pages:

2
Author:

rezancuk2j

Gene amplification It is an increase in copy number of a restricted region of a chromosome increasing the is the quantity of DNA in these regions. It is a mechanism that cancer cells use to escape resistance from methotrexate whereby the target gene, dihydrofolate reductase, is amplified. It is also a mechanism by which breast tumor cells progress and become more aggressive whereby they amplify the human epidermal growth factor receptor 2 (HER2), which stimulates cell growth. cell

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