The Muscular System: Sliding Filament Theory 1. a. The thick filament is composed of what molecule? myosin _______________________ b. Flexing the head of this molecule provides what is known as the "power stroke" _________________________. 2. 3. The myosin head contains binding sites for what two molecules? a. ATP b. actin Three molecules make up the thin filament. a. Which molecule has a binding site for myosin heads? actin _____________________________ b. Which molecule covers this binding site? tropomyosin _________________________________________________ c. Which molecule has a binding site for calcium ions? troponin ______________________________________ 4. What molecule must bind to the myosin head in order for it to disconnect with ATP actin? _________________________ 5. Hydrolysis of the molecule in question 4 returns the myosin molecule to the _________________________ confirmation. high-energy 6. Binding of the myosin heads sequentially prevents _____________________ back sliding of the thin filament. 7. Name three roles for ATP in the contraction of muscle. a. Energizes the "power stroke" of the myosin cross bridge b. Disconnects the myosin heads for the binding sites in actin after the "power stroke" c. Actively transports calcium ions into the sarcoplasmic reticulum 8. actin What molecule is connected to the Z line? _________________________ 9. Which of the following shorten during contraction? (may be more than one) a. Thin filament b. Sarcomere c. H zone d. Thick filament 10. a. What is the name of the condition in which muscles become rigid after death? _________________________________ Rigor Mortis b. What is this condition due to? The body stiffens after death because the muscles are losing ATP

Sliding Filament Theory Worksheet

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