Med Diet Study

Med Diet ●​ High in ○​ Fruit ○​ Vegetables ○​ Whole grains ○​ Legumes ○​ Nuts and seeds ●​ Health benefits ○​ Reduce CVD ○​ Blood sugar control ■​ Preventing type 2 diabetes ○​ Lower inflammation ○​ Protection against Alzheimer ○​ Weight managements ●​ Whole minimally processed food ○​ High fibers, healthy fats ■​ Anti-inflammatory ■​ Healthy digestive system PREDIMED study 2013 ●​ Randomized trial of 7500 high risk individuals in Spain ●​ Provide 3 diets 1.​ Mediterranean + extra virgin olive oil 2.​ Mediterranean + nuts 3.​ Low- fat control diet ●​ Mediterranean diet group had reduced risk of cardiovascular disease by 30% Current evidence does not support the use of nutritional supply ●​ Mineral supplements are advertised to reduce risk of( multivitamins , Omega-3 Vitamine D, Vitamin C) ○​ Cardiovascular disease ○​ Cancer ○​ Mortality ●​ Cocharne meta-analysis shows supplements such as antioxidants does not prevent chronic disease ●​ Diet insead, shows benefit repetitively ANN INTERN MED ●​ Lack of benefit ○​ Multivitamins and mineral supplements does not reduce risk of CVD ●​ Potential Harm ○​ Some are taken in High dose ○​ May be detrimental ○​ Beta-carotene and vitamine E associated could increase risk of mortality Role of vitamine D in Cardiometabolic disease ●​ Pancreatic B cells ○​ Affects insuline secretion ●​ Muscle adipose tissue ○​ insulin sensitivity ●​ Cardio myoctes/vascular endothelium ○​ inflammation and blood pressure Low Vitamin D increased insuline resistance with Chronic inflammation Randomized Controlled Trials (RCTs) ●​ Researched on 25,871 adults ●​ intervention of Vitamin D3 ●​ Other group given with placebo ●​ No significant major cardiovascular event ○​ No stoke, myocardial infraction ○​ No cancer deaths